Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
465-04-013 ISMRM Abstract

Anatomically-Guided Deep Learning for Early Parkinson's Disease Diagnosis Using Dual-Modal Diffusion MRI

Accepted
Yu Shen 1, Yan Bai1, 亚平 吴1, Wei Wei1, Xinhui Wang1,2, xianchang zhang3, Meiyun Wang1
1Department of Radiology, Zhengzhou University People's Hospital & Henan Provincial People's Hospital, Zhengzhou, China
2Zhengzhou University People's Hospital & Henan Provincial People's Hospital, Zhengzhou, China
3MR Collaborations, Beijing, China
Presenting Author: Yu Shen

Synopsis

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References

1. Dorsey ER, Elbaz A, Nichols E, Abd-Allah F, Abdelalim A, Adsuar JC, Ansha MG, Brayne C, Choi JYJ, Collado-Mateo D et al (2018) Global, regional, and national burden of Parkinson's disease, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet Neurol 17(11):939-953. http://doi.org/10.1016/s1474-4422(18)30295-3. [doi]
2. Tolosa E, Garrido A, Scholz SW, Poewe W (2021) Challenges in the diagnosis of Parkinson's disease. The Lancet Neurology 20(5):385-397. http://doi.org/10.1016/s1474-4422(21)00030-2. [doi]
3. Rizzo G, Copetti M, Arcuti S, Martino D, Fontana A, Logroscino G (2016) Accuracy of clinical diagnosis of Parkinson disease: A systematic review and meta-analysis. Neurology 86(6):566-576. http://doi.org/10.1212/wnl.0000000000002350. [doi]
4. Beach TG, Adler CH (2018) Importance of low diagnostic Accuracy for early Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society 33(10):1551-1554. http://doi.org/10.1002/mds.27485. [doi]
5. Zhang D, Zhou L, Lu C, Feng T, Liu J, Wu T (2024) Free-Water Imaging of the Nucleus Basalis of Meynert in Patients With Idiopathic REM Sleep Behavior Disorder and Parkinson Disease. Neurology 102(7):e209220. http://doi.org/10.1212/wnl.0000000000209220. [doi]
6. Zhao H, Tsai CC, Zhou M, Liu Y, Chen YL, Huang F, Lin YC, Wang JJ (2022) Deep learning based diagnosis of Parkinson's Disease using diffusion magnetic resonance imaging. Brain imaging and behavior 16(4):1749-1760. http://doi.org/10.1007/s11682-022-00631-y. [doi]
7. Yang MJ, Huang XB, Huang LQ, Cai GE (2023) Diagnosis of Parkinson's disease based on 3D ResNet: The frontal lobe is crucial. BIOMEDICAL SIGNAL PROCESSING AND CONTROL 85. http://doi.org/10.1016/j.bspc.2023.104904. [doi]
8. Dolz J, Gopinath K, Yuan J, Lombaert H, Desrosiers C, Ben Ayed I (2019) HyperDense-Net: A Hyper-Densely Connected CNN for Multi-Modal Image Segmentation. IEEE Trans Med Imaging 38(5):1116-1126. http://doi.org/10.1109/tmi.2018.2878669. [doi]
9. Wang LH, Qi CC, Ou CB, An L, Jin M, Kong XB, Li XM (2025) MultiEYE: Dataset and Benchmark for OCT-Enhanced Retinal Disease Recognition From Fundus Images. IEEE Trans Med Imaging 44(4):1711-1722. http://doi.org/10.1109/tmi.2024.3518067. [doi]
10. Chandra Joshi R, Kumar Sharma A, Kishore Dutta M (2024) VisionDeep-AI: Deep learning-based retinal blood vessels segmentation and multi-class classification framework for eye diagnosis. Biomedical Signal Processing and Control 94:106273. http://doi.org/https://doi.org/10.1016/j.bspc.2024.106273. [doi]
11. Chen X, Zhou B, Xie H, Guo X, Zhang J, Duncan JS, Miller EJ, Sinusas AJ, Onofrey JA, Liu C (2023) DuSFE: Dual-Channel Squeeze-Fusion-Excitation co-attention for cross-modality registration of cardiac SPECT and CT. Medical Image Analysis 88:102840. http://doi.org/https://doi.org/10.1016/j.media.2023.102840. [doi]

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