Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
607-02-002 ISMRM Abstract

Flip Angle Modulation with Extended Readout for Co-Localized PDFF, R2*, and T1-Weighted Images

Primary: Contrast Mechanisms - Multi-Contrast
Secondary: Acquisition & Reconstruction - Pulse Sequence Design: Non-Neuro
607-02-002 · Quantitative and Multi-Contrast MRI: Methods and Applications · Thursday, 14 May, 1:40 PM–3:30 PM · Meeting Room 1.40
Keywords: Acquisition Methods Liver Quantitative Imaging Proton density fat fraction (PDFF) T1
Accepted
Jiayi Tang 1,2, Daiki Tamada2, Amirhossein Roshanshad2, Jitka Starekova2, Jon-Fredrik Nielsen3, Maxim Zaitsev4, Scott B Reeder1,2,5,6,7, Diego Hernando1,2
1Department of Medical Physics, University of Wisconsin - Madison, Madison, United States of America
2Department of Radiology, University of Wisconsin - Madison, Madison, United States of America
3Department of Radiology, University of Michigan, Ann Arbor, United States of America
4Division of Medical Physics, Department of Diagnostic and Interventional Radiology, University Medical Center Freiburg, Freiburg, Germany
5Department of Biomedical Engineering, University of Wisconsin - Madison, Madison, United States of America
6Department of Medicine, University of Wisconsin - Madison, Madison, United States of America
7Department of Emergency Medicine, University of Wisconsin - Madison, Madison, United States of America
Presenting Author: Jiayi Tang

Synopsis

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References

1. Zhao R, Zhang Y, Wang X, et al. Motion-robust, high-SNR liver fat quantification using a 2D sequential acquisition with a variable flip angle approach. Magn Reson Med. 2020;84(4):2004-2017. doi:10.1002/mrm.28263 [doi]
2. Tang J, Tamada D, do Vale Souza R, et al. Optimized motion-insensitive PDFF mapping of the liver. Magn Reson Med. September 2025. doi:10.1002/mrm.70047 [doi]
3. Layton KJ, Kroboth S, Jia F, et al. Pulseq: A rapid and hardware-independent pulse sequence prototyping framework. Magn Reson Med. 2017;77(4):1544-1552. doi:10.1002/mrm.26235 [doi]
4. Nielsen JF, Noll DC. TOPPE: A framework for rapid prototyping of MR pulse sequences. Magn Reson Med. 2018;79(6):3128-3134. doi:10.1002/mrm.26990 [doi]
5. Hernando D, Hines CDG, Yu H, Reeder SB. Addressing phase errors in fat-water imaging using a mixed magnitude/complex fitting method. Magn Reson Med. 2012;67(3):638-644. doi:10.1002/mrm.23044 [doi]
6. Campo CA, Hernando D, Schubert T, Bookwalter CA, Pay AJV, Reeder SB. Standardized Approach for ROI-Based Measurements of Proton Density Fat Fraction and R2* in the Liver. AJR Am J Roentgenol. 2017;209(3):592-603. doi:10.2214/AJR.17.17812 [doi]
7. Heidenreich JF, Tang J, Tamada D, et al. Motion-Insensitive Flip Angle Modulated Liver Proton Density Fat-Fraction and R2* Mapping During Free-Breathing MRI in a Clinical Setting. J Magn Reson Imaging. July 2025. doi:10.1002/jmri.70033 [doi]
8. Tang J, Tamada D, Starekova J, et al. Bipolar Readouts Improve Quantitative Performance of Motion-Robust, Flip-Angle Modulated PDFF and R2* Mapping at High R2*. In: Proceedings of the International Society for Magnetic Resonance in Medicine. Honolulu, HI, USA; 2025:3215.
9. Wang JH, Tang J, Tamada D, et al. Bipolar Flip Angle Modulated Chemical Shift Encoded Imaging Enabled with Gradient Impulse Response Function. In: Proceedings of the International Society for Magnetic Resonance in Medicine. Honolulu, HI, USA; 2025:2624.

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/607-02-002