Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
461-05-007 ISMRM Abstract

Feasibility of Simultaneous CSF-STREAM–EEG at 7T: Toward Mapping of Sleep-Dependent CSF-Dynamics

Primary: Neuro - Neurofluids
Secondary: Physics & Engineering - Safety
461-05-007 · Advances in Neuroimaging and Biomarkers for Brain Health and Disease · Tuesday, 12 May, 4:00 PM–4:55 PM · Digital Posters Row B
Keywords: CSF-STREAM 7T MRI EEG-MRI correction EEG-MRI integration CSF Dynamics
Accepted
Balázs Örzsik 1, Emiel Roefs1, Nina Fultz1, Madda Debiasi1, Rolf Fronczek2,3, Lydiane Hirschler1, Matthias van Osch1
1C.J. Gorter MRI Center, Department of Radiology, Leiden University Medical Center, Leiden, Netherlands
2Department of Neurology, Leiden University Medical Center, Leiden, Netherlands
3Sleep-Wake Centre, Stichting Epilepsie Instellingen Nederland, Heemstede, Netherlands
Presenting Author: Balázs Örzsik

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References

1. Iliff, J.J. et al. (2012) ‘A paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid β’, Science Translational Medicine, 4(147). doi:10.1126/scitranslmed.3003748. [doi]
2. Xie, L. et al. (2013) ‘Sleep drives metabolite clearance from the adult brain’, Science, 342(6156), pp. 373–377. doi:10.1126/science.1241224. [doi]
3. Fultz, N.E. et al. (2019) ‘Coupled electrophysiological, hemodynamic, and cerebrospinal fluid oscillations in human sleep’, Science, 366(6465), pp. 628–631. doi:10.1126/science.aax5440. [doi]
4. Picchioni, D. et al. (2022) ‘Autonomic arousals contribute to brain fluid pulsations during sleep’, NeuroImage, 249, p. 118888. doi:10.1016/j.neuroimage.2022.118888. [doi]
5. Setzer, B. et al. (2022) ‘A temporal sequence of thalamic activity unfolds at transitions in behavioral arousal state’, Nature Communications, 13(1). doi:10.1038/s41467-022-33010-8. [doi]
6. Yun C-S et al. (2025) Feasibility of observing glymphatic system activity during sleep using diffusion tensor imaging analysis along the perivascular space (DTI-ALPS) index. Diagnostics 15(14):1798. doi:10.3390/diagnostics15141798 [doi]
7. Hirschler L et al. (2025) Region-specific drivers of CSF mobility measured with MRI in humans. Nat Neurosci. doi:10.1038/s41593-025-02073-3 [doi]
8. Niazy, R.K. et al. (2005) ‘Removal of FMRI environment artifacts from EEG data using optimal basis sets’, NeuroImage, 28(3), pp. 720–737. doi:10.1016/j.neuroimage.2005.06.067. [doi]
9. van der Meer, J.N. et al. (2016) ‘Carbon-wire loop based artifact correction outperforms post-processing EEG/fmri corrections—a validation of a real-time simultaneous EEG/fmri correction method’, NeuroImage, 125, pp. 880–894. doi:10.1016/j.neuroimage.2015.10.064. [doi]

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http://echo.ismrm.org/p/ISMRM2026/461-05-007