Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
470-11-162 ISMRM Abstract

Metabolic Profiling with BrainSpec MRS Reveals Changes after Hematopoietic Stem Cell Transplantation in Pediatric ALD

Primary: Acquisition & Reconstruction - Spectroscopy and spectroscopic imaging
Secondary: Pediatrics - Neuro
470-11-162 · Spectroscopy Traditional Posters · Tuesday, 12 May, 4:55 PM–5:50 PM · Traditional Posters | Exhibition Hall
Keywords: Analysis/Processing MR Spectroscopy (MRS) Stem cell transplantation Chemical Shift Imaging (CSI) X-linked Adrenoleukodystrophy
Accepted
Eva-Maria Ratai 1,2, Lasya P Sreepada3,4, Samir Reddigari4, Luna Rohm2, Philippa Schunk2, Damilola Oje5, Yedda Li5, Amanda Nagy5, Melissa Bambery5, Alexander P Lin3,4, Alexandra Zimmerman4, Florian Eichler5,6
1Harvard Medical School, Boston, United States of America
2Department of Radiology, Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School, Charlestown, United States of America
3Brigham and Women's Hospital and Harvard Medical School, Boston, United States of America
4BrainSpec, Boston, United States of America
5Neurology, Massachusetts General Hospital, Boston, United States of America
6Department of Neurology, Harvard Medical School, Boston, United States of America
Presenting Author: Eva-Maria Ratai

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References

1. 1. Aryal, S., Sharma, S., Poudel, S., & Sharma, S. (2022). Role of MRI in X-linked adrenoleukodystrophy-A case report. Radiology case reports, 17(11), 4403–4407. https://doi.org/10.1016/j.radcr.2022.08.052 [doi]
2. 2. Eichler, F. S., Barker, P. B., Cox, C., Edwin, D., Ulug, A. M., Moser, H. W., & Raymond, G. V. (2002). Proton MR spectroscopic imaging predicts lesion progression on MRI in X-linked adrenoleukodystrophy. Neurology, 58(6), 901–907. https://doi.org/10.1212/wnl.58.6.901 [doi]
3. 3. Ratai E, Kok T, Wiggins C, Wiggins G, Grant E, Gagoski B, O'Neill G, Adalsteinsson E, Eichler F. Seven-Tesla proton magnetic resonance spectroscopic imaging in adult X-linked adrenoleukodystrophy. Arch Neurol. 2008 Nov;65(11):1488-94. https://doi.org/10.1001/archneur.65.11.1488 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/470-11-162