130-03-001 ISMRT Abstract

Exploring the Prevalence of Myocardial Steatosis in Women with HIV on ART: Preliminary findings from the MUTIMA Study

130-03-001 · Winning Research Oral Presentations · Saturday, 9 May, 10:20 AM–10:50 AM · Meeting Room 2.60

Keywords: Myocardial remodeling Late gadolinium enhancement Fat infiltration HIV Magnetic resonance spectroscopic imaging

Accepted

Petronella Samuels ¹, Olukayode Aremu^2,3,4, Morné Kahts^2,5,6, Patricia Maishi^7,8, MARIAAN JAFTHA¹, Natasha Taylor-Meyer^2,3, Marguerite Adriaanse^2,3, Sango Skelem^2,3, Stephen Jermy^7,9,10,11, Lidia Szczepaniak¹², Boni Ale¹³, Markella Zanni¹⁴, Chris Longenecker¹³, Ntobeko Ntusi^1,2,3,4

¹Cape Universities Body Imaging Centre (CUBIC), University of Cape Town, Cape Town, South Africa

²Cape Heart Institute, Department of Medicine, University of Cape Town, Cape Town, South Africa

³Division of Cardiology, University of Cape Town and Groote Schuur Hospital, Cape Town, South Africa

⁴South African Medical Research Council Extramural Unit on Intersection of Noncommunicable Diseases and Infectious Diseases, Cape Town, South Africa

⁵South African Medical Research Council, Cape Town, South Africa

⁶Division of Radiology, Department of Radiation Medicine, University of Cape Town and Groote Schuur Hospital, Cape Town, South Africa

⁷University of Cape Town, Cape Town, South Africa

⁸CUBIC, Cape Universities Body Imaging Centre (CUBIC), University of Cape Town, Cape Town, South Africa

⁹Human Biology, University of Cape Town, Cape Town, South Africa

¹⁰Neuroscience Institute, University of Cape Town, Cape Town, South Africa

¹¹CUBIC, University of Cape Town, Cape Town, South Africa

¹²MRS Consulting in Biomedical Research, Albuquerque, NM,, United States of America

¹³School of Medicine and Department of Global Health, University of Washington, Washington, United States of America

¹⁴Massachusetts General Hospital and Harvard Medical School, Boston, United States of America

Presenting Author: Petronella Samuels

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References

1. Chen, Y., et al., Human Immunodeficiency Virus Infection and Incident Heart Failure: A Meta-Analysis of Prospective Studies. J Acquir Immune Defic Syndr, 2021. 87(1): p. 741-749. DOI: 10.1097/QAI.0000000000002629 [doi]

2. 3. Butler J, Kalogeropoulos AP, Anstrom KJ, Hsue PY, Kim RJ, Scherzer R, Shah SJ, Shah SH, Velazquez EJ, Hernandez AF, Desvigne-Nickens P, Braunwald E. Diastolic Dysfunction in Individuals With Human Immunodeficiency Virus Infection: Literature Review, Rationale and Design of the Characterizing Heart Function on Antiretroviral Therapy (CHART) Study. J Card Fail. 2018 Apr;24(4):255-265. DOI: 10.1016/j.cardfail.2018.02.001 [doi]

3. Writing Committee, M., et al., 2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure: Executive Summary: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. J Am Coll Cardiol, 2022. https://doi.org/10.1161/CIR.0000000000001063 [doi]

4. Oneglia AP, Szczepaniak LS, Jaffery MF, Cipher DJ, McDonald JG, Haykowsky MJ, Moreau KL, Clegg DJ, Zaha V, Nelson MD. Myocardial steatosis impairs left ventricular diastolic-systolic coupling in healthy humans. J Physiol. 2023 Apr;601(8):1371-1382. DOI: 10.1113/JP284272 [doi]

5. Neilan TG, Nguyen KL, Zaha VG, Chew KW, Morrison L, Ntusi NAB, Toribio M, Awadalla M, Drobni ZD, Nelson MD, Burdo TH, Van Schalkwyk M, Sax PE, Skiest DJ, Tashima K, Landovitz RJ, Daar E, Wurcel AG, Robbins GK, Bolan RK, Fitch KV, Currier JS, Bloomfield GS, Desvigne-Nickens P, Douglas PS, Hoffmann U, Grinspoon SK, Ribaudo H, Dawson R, Goetz MB, Jain MK, Warner A, Szczepaniak LS, Zanni MV. Myocardial Steatosis Among Antiretroviral Therapy-Treated People With Human Immunodeficiency Virus Participating in the REPRIEVE Trial. J Infect Dis. 2020 Jul 9;222(Suppl 1):S63-S69. DOI: 10.1093/infdis/jiaa245 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/130-03-001