Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
651-02-006 / 651-02-006 ISMRM Abstract

A fusion model of time-dependent diffusion MRI and serum biomarkers for differentiating ICC from HCC: a preliminary study

Primary: Diffusion - Microstructure
Secondary: Body - Liver
651-02-006 · Diffusion Modeling To Map Tissue Microstructure · Thursday, 14 May, 1:40 PM–3:16 PM · Power Pitch Theatre 1
651-02-006 · Diffusion Modeling To Map Tissue Microstructure · Thursday, 14 May, 1:40 PM–3:16 PM · Power Pitch Theatre 1
Keywords: Hepatocellular carcinoma Intrahepatic cholangiocarcinoma Time-dependent diffusion MRI Serum biomarker Gadoxetate disodium-enhanced MRI
Accepted
Xingqing Qin 1, Jin-yuan Liao1, Yu-chen Wei1, Yong-mei Huang1, Yan-yan YU1, Hui Zhang2, Thorsten Feiweier3, Meining Chen2
1Department of Radiology, The First Affiliated Hospital of Guangxi Medical University,, Nanning, China
2MR Research Collaboration Team, Shanghai, China
3MR Research & Clinical Translation, Erlangen, Germany
Presenting Author: Xingqing Qin

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References

1. Schieda N, Maralani PJ, Hurrell C, Tsampalieros AK, Hiremath S. Updated Clinical Practice Guideline on Use of Gadolinium-Based Contrast Agents in Kidney Disease Issued by the Canadian Association of Radiologists. Canadian Association of Radiologists Journal-Journal De L Association Canadienne Des Radiologistes. 2019;70(3):226-32.
2. Qi F, Zhou A, Yan L, Yuan X, Wang D, Chang R, et al. The diagnostic value of PIVKA-II, AFP, AFP-L3, CEA, and their combinations in primary and metastatic hepatocellular carcinoma. J Clin Lab Anal. 2020;34(5):e23158.
3. Kele PG, van der Jagt EJ. Diffusion weighted imaging in the liver. World Journal of Gastroenterology. 2010;16(13):1567-76.
4. Peng J, Zheng J, Yang C, Wang R, Zhou Y, Tao Y-Y, et al. Intravoxel incoherent motion diffusion-weighted imaging to differentiate hepatocellular carcinoma from intrahepatic cholangiocarcinoma. Scientific Reports. 2020;10(1).
5. Jiang X, Xu J, Gore JC. Mapping hepatocyte size in vivo using temporal diffusion spectroscopy MRI. Magn Reson Med. 2020;84(5):2671-83.
6. Partridge SC, Xu J. Cellular Characterization of Breast Cancer Using Microstructural Diffusion MRI. Radiology. 2024;313(1).
7. Wu D, Jiang K, Li H, Zhang Z, Ba R, Zhang Y, et al. Time-Dependent Diffusion MRI for Quantitative Microstructural Mapping of Prostate Cancer. Radiology. 2022;303(3):578-87.
8. Jiang X, Xu J, Gore JC. Mapping hepatocyte size in vivo using temporal diffusion spectroscopy MRI. Magnetic Resonance in Medicine. 2020;84(5):2671-83.
9. Vyas M, Jain D. An update on subtypes of hepatocellular carcinoma: From morphology to molecular. Indian Journal of Pathology and Microbiology. 2021;64(5):112-20.
10. Wei M, Lü L, Lin P, Chen Z, Quan Z, Tang Z. Multiple cellular origins and molecular evolution of intrahepatic cholangiocarcinoma. Cancer Lett. 2016;379(2):253-61.
11. Calderaro J, Ziol M, Paradis V, Zucman-Rossi J. Molecular and histological correlations in liver cancer. J Hepatol. 2019;71(3):616-30.
12. Katabathina VS, Khanna L, Surabhi VR, Minervini M, Shanbhogue K, Dasyam AK, et al. Morphomolecular Classification Update on Hepatocellular Adenoma, Hepatocellular Carcinoma, and Intrahepatic Cholangiocarcinoma. Radiographics. 2022;42(5):1338-57.

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http://echo.ismrm.org/p/ISMRM2026/651-02-006