Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
466-01-012 ISMRM Abstract

Dynamic Evaluation of Tumor Microenvironment during Anti-angiogenic Therapy in Colorectal Cancer using Multi-parametric MRI

Primary: Body - Digestive
Secondary: Brain Function and fMRI - fMRI Analysis
466-01-012 · Rectal Cancer · Tuesday, 12 May, 8:20 AM–9:15 AM · Digital Posters Row G
Keywords: Diffusion-Weighted Imaging Colorectal cancer Dynamic Contrast-enhanced Imaging Amide Proton Transfer Imaging.
Accepted
Lingtao Zhang 1, Wenfeng Mai1, wei cui2, Dong Zhang1,3, Liangping Luo1,3,4, Changzheng Shi1,3
1Medical Imaging Center, The First Affiliated Hospital of Jinan University, Guangzhou, China
2MRI Research, GE Healthcare, Beijing, China
3The Guangzhou Key Laboratory of Molecular and Functional Imaging for Clinical Translation, The First Affiliated Hospital of Jinan University, Guangzhou, China
4Department of Radiology and Nuclear Medicine, The Fifth Affiliated Hospital of Jinan University (Shenhe People’s Hospital), China
Presenting Author: Lingtao Zhang

Synopsis

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References

1. Hu X, Ye K, Bo S, et al. Monitoring imatinib decreasing pericyte coverage and HIF-1α level in a colorectal cancer model by an ultrahigh-field multiparametric MRI approach. J Transl Med. 2024;22(1):712.
2. Ioannou M, Paraskeva E, Baxevanidou K, et al. HIF-1alpha in colorectal carcinoma: review of the literature. J BUON, 2015, 20: 680-9.
3. Lyssiotis CA, Kimmelman AC. Metabolic Interactions in the Tumor Microenvironment. Trends Cell Biol, 2017;27:863-875.
4. Huang YS, Chen JL, Chen HM, et al. Assessing tumor angiogenesis using dynamic contrast-enhanced integrated magnetic resonance-positron emission tomography in patients with non-small-cell lung cancer. BMC Cancer, 2021, 21: 348.
5. Shi X, Yang W, Ma Q, et al. Hemoglobin-mediated biomimetic synthesis of paramagnetic O(2)-evolving theranostic nanoprobes for MR imaging-guided enhanced photodynamic therapy of tumor. Theranostics, 2020, 10(25): 11607-21.

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/466-01-012