Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
468-02-003 ISMRM Abstract

Thalamic subregions link Type 2 Diabetes Mellitus to slowed processing speed: UK Biobank evidence with Jinan validation

Accepted
Fushuai Zhang 1, Nan Zhang2, Yenan Che3, Zhenyu Cheng1, Xinxin Huo2, Boyao Chen3, Pengcheng Liang2, Yiwen Chen2, Jiaxiang xin4, Meng Li5, Lingfei Guo3
1Binzhou Medical University, Yantai City, Shandong Province, China
2Department of Radiograpy, Shandong Provincial Hospital Affiliated to Shandong First Medical University (Shandong Provincial Hospital), Jinan, China
3Shandong Provincial Hospital Affiliated to Shandong First Medical University (Shandong Provincial Hospital), Jinan, China
4MR Collaborations, Siemens Healthineers Ltd., Shanghai, China
5Jena University Hospital, Jena, Germany
Presenting Author: Fushuai Zhang

Synopsis

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References

1. Spauwen PJ, Köhler S, Verhey FR, Stehouwer CD, van Boxtel MP. Effects of type 2 diabetes on 12-year cognitive change: results from the Maastricht Aging Study. Diabetes Care. 2013 Jun;36(6):1554-61. doi: 10.2337/dc12-0746. Epub 2012 Dec 28. PMID: 23275366; PMCID: PMC3661848. [doi] [pmid]
2. Chen J, Zhang J, Liu X, Wang X, Xu X, Li H, Cao B, Yang Y, Lu J, Chen Z. Abnormal subcortical nuclei shapes in patients with type 2 diabetes mellitus. Eur Radiol. 2017 Oct;27(10):4247-4256. doi: 10.1007/s00330-017-4790-3. Epub 2017 Apr 3. PMID: 28374074. [doi] [pmid]
3. Shah SN, Dounavi ME, Malhotra PA, Lawlor B, Naci L, Koychev I, Ritchie CW, Ritchie K, O'Brien JT. Dementia risk and thalamic nuclei volumetry in healthy midlife adults: the PREVENT Dementia study. Brain Commun. 2024 Feb 15;6(2):fcae046. doi: 10.1093/braincomms/fcae046. PMID: 38444908; PMCID: PMC10914447. [doi] [pmid]
4. Arnts H, Coolen SE, Fernandes FW, Schuurman R, Krauss JK, Groenewegen HJ, van den Munckhof P. The intralaminar thalamus: a review of its role as a target in functional neurosurgery. Brain Commun. 2023 Feb 2;5(3):fcad003. doi: 10.1093/braincomms/fcad003. PMID: 37292456; PMCID: PMC10244065. [doi] [pmid]
5. Wang XD, Chen C, Zhang D, Yao H. Cumulative latency advance underlies fast visual processing in desynchronized brain state. Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):515-20. doi: 10.1073/pnas.1316166111. Epub 2013 Dec 17. PMID: 24347634; PMCID: PMC3890836. [doi] [pmid]

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