Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
566-01-004 ISMRM Abstract

Arterial spin labeling assessments of cerebral blood flow reflect antisocial behavior symptoms in frontotemporal dementia

Accepted
Behnaz Akbarian1, Kilian Hett2, Paula Trujillo 2, Ciaran Considine2, Simon Vandekar3, Manus J Donahue2, Ryan Darby2
1Vanderbilt University, Nashville, United States of America
2Department of Neurology, Vanderbilt University Medical Center, Nashville, United States of America
3Department of Biostatistics, Vanderbilt University Medical Center, Nashville, United States of America
Presenting Author: Paula Trujillo

Synopsis

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References

1. Mollah SA, Nayak A, Barhai S, Maity U. A comprehensive review on frontotemporal dementia: its impact on language, speech and behavior. Dement Neuropsychol. 2024;18:e20230072. doi:10.1590/1980-5764-dn-2023-0072 [doi]
2. Ratnavalli E, Brayne C, Dawson K, Hodges JR. The prevalence of frontotemporal dementia. Neurology. 2002;58(11):1615-1621. doi:10.1212/WNL.58.11.1615 [doi]
3. Liljegren M, Naasan G, Temlett J, et al. Criminal Behavior in Frontotemporal Dementia and Alzheimer Disease. JAMA Neurol. 2015;72(3):295. doi:10.1001/jamaneurol.2014.3781 [doi]
4. Mendez MF, Chen AK, Shapira JS, Miller BL. Acquired Sociopathy and Frontotemporal Dementia. Dement Geriatr Cogn Disord. 2005;20(2-3):99-104. doi:10.1159/000086474 [doi]
5. Miller BL, Darby A, Benson DF, Cummings JL, Miller MH. Aggressive, socially disruptive and antisocial behaviour associated with fronto-temporal dementia. Br J Psychiatry. 1997;170(2):150-155. doi:10.1192/bjp.170.2.150 [doi]
6. Achenbach TM, Dumenci L, Rescorla LA. Ratings of Relations Between DSM-IV Diagnostic Categories and Items of the Adult Self-Report (ASR) and Adult Behavior Checklist (ABCL).
7. Tremblay RE. Developmental origins of disruptive behaviour problems: the ‘original sin’ hypothesis, epigenetics and their consequences for prevention. J Child Psychol Psychiatry. 2010;51(4):341-367. doi:10.1111/j.1469-7610.2010.02211.x [doi]
8. Brigidi BD, Achenbach TM, Dumenci L, Newhouse PA. Broad spectrum assessment of psychopathology and adaptive functioning with the Older Adult Behavior Checklist: a validation and diagnostic discrimination study. Int J Geriatr Psychiatry. 2010;25(11):1177-1185. doi:10.1002/gps.2459 [doi]
9. Salmon D, Filoteo J. Neuropsychology of Cortical versus Subcortical Dementia Syndromes. Semin Neurol. 2007;27(1):007-021. doi:10.1055/s-2006-956751 [doi]
10. Huang CC, Rolls ET, Feng J, Lin CP. An extended Human Connectome Project multimodal parcellation atlas of the human cortex and subcortical areas. Brain Struct Funct. 2022;227(3):763-778. doi:10.1007/s00429-021-02421-6 [doi]
11. Alsop DC, Detre JA, Golay X, et al. Recommended implementation of arterial spin‐labeled perfusion MRI for clinical applications: A consensus of the ISMRM perfusion study group and the European consortium for ASL in dementia. Magn Reson Med. 2015;73(1):102-116. doi:10.1002/mrm.25197 [doi]

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