Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
461-01-003 ISMRM Abstract

Towards Imaging Microbubble Contrast Agents with MRI: Simulation, Phantom, and Pre-clinical Results

Primary: Contrast Mechanisms - Contrast Agents
Secondary: Cardiovascular - Myocardium
461-01-003 · Cardiac Tissue Characterization · Tuesday, 12 May, 8:20 AM–9:15 AM · Digital Posters Row B
Keywords: Simulations Contrast Agents Microstructure Myocardium Animal mouse model
Accepted
Milo M Commandeur1, Ayda Arami 1,2,3, Elias Ylä-Herttuala4,5, Yi Zhang1, Qian Tao1, Alexandru Cernicanu6, Iida Räty4, Maarit Pulkkinen7, Hildo J Lamb2, Sebastian Weingärtner1,3
1Imaging Physics, TU Delft, Delft, Netherlands
2Radiology, LUMC, Leiden, Netherlands
3Holland PTC, Delft, Netherlands
4A.I. Virtanen Institute, University of Eastern Finland, Kuopio, Finland
5Department of Medicine, University of Eastern Finland, Kuopio, Finland
6Philips Benelux, Eindhoven, Netherlands
7A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland
Presenting Author: Ayda Arami

Synopsis

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References

1. Wong, K. K., Huang, I., Kim, Y. R., Tang, H., Yang, E. S., Kwong, K. K., & Wu, E. X. (2004). In vivo study of microbubbles as an MR susceptibility contrast agent. Magnetic Resonance in Medicine, 52(3), 445–452. https://doi.org/10.1002/mrm.20181 [doi]
2. Kurz, F. T., Kampf, T., Heiland, S., Bendszus, M., Schlemmer, H. P., & Ziener, C. H. (2014). Theoretical model of the single spin-echo relaxation time for spherical magnetic perturbers. Magnetic Resonance in Medicine, 71(5), 1888–1895. https://doi.org/10.1002/mrm.25196 [doi]
3. Spear, J. T., & Gore, J. C. (2014). Effects of diffusion in magnetically inhomogeneous media on rotating frame spin-lattice relaxation. Journal of Magnetic Resonance, 249, 80–87. https://doi.org/10.1016/j.jmr.2014.10.003 [doi]
4. Bjrnerud, A., Johansson, L. O., Briley-Sb, K., & Ahlstrm, H. K. (2002). Assessment of T1 and T2* effects in vivo and ex vivo using iron oxide nanoparticles in steady state - Dependence on blood volume and water exchange. Magnetic Resonance in Medicine, 47(3), 461–471. https://doi.org/10.1002/mrm.10066 [doi]
5. Storey, P., & Novikov, D. S. (2024). Signatures of microstructure in gradient-echo and spin-echo signals. Magnetic Resonance in Medicine, 92(1), 269–288. https://doi.org/10.1002/mrm.30022 [doi]
6. Khatiwada, R., Dennis, L., Kendrick, R., Khosravi, M., Peters, M., Smith, E., & Snow, M. (2015). Materials with low DC magnetic susceptibility for sensitive magnetic measurements. https://doi.org/10.1088/0957-0233/27/2/025902 [doi]
7. Palanisamy, G. (2017). A Case Study on Runge Kutta 4 th Order Differential Equations and Its Application. https://www.researchgate.net/publication/320124650

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/461-01-003