Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
465-05-003 ISMRM Abstract

Microstructural Health is Severely Compromised upon WMH Load Beyond a Threshold

Primary: Diffusion - Microstructure
Secondary: Diffusion - Tractography
465-05-003 · Tractography Applications · Tuesday, 12 May, 4:00 PM–4:55 PM · Digital Posters Row F
Keywords: Aging White matter hyperintensity Diffusivity along white matter tracts Diffusion Tensor Imaging (DTI) White matter microstructure
Accepted
Smarak Das 1, Neha Yadav2, Niraj K Gupta1,2, Vivek Tiwari1,2
1Indian Institute of Science Education and Research (IISER) Berhampur, Odisha, India
2Department of Biological Sciences, Indian Institute of Science Education and Research (IISER) Berhampur, Odisha, India
Presenting Author: Smarak Das

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References

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6. Jennifer K Ferris, Julia Dahlby, Shie Rinat, Brian Greeley, Joel Ramirez, Sandra E Black, Lara A Boyd, Sensitivity of diffusion tensor imaging to regional mixed cerebrovascular pathology, Brain Communications, Volume 7, Issue 3, 2025, fcaf193, https://doi.org/10.1093/braincomms/fcaf193 [doi]
7. Zhuang, Feng-Juan1,#; Chen, Yan1,#; He, Wen-Bo1; Cai, Zhi-You MD, PhD2,*. Prevalence of white matter hyperintensities increases with age. Neural Regeneration Research 13(12):p 2141-2146, December 2018. | DOI: 10.4103/1673-5374.241465 [doi]
8. Yadav, N., Gupta, N.K., Thakar, D. et al. Magnitude and kinetics of a set of neuroanatomic volume and thickness together with white matter hyperintensity is definitive of cognitive status and brain age. Transl Psychiatry 14, 389 (2024). https://doi.org/10.1038/s41398-024-03097-2 [doi]
9. Yeh, FC. Population-based tract-to-region connectome of the human brain and its hierarchical topology. Nat Commun 13, 4933 (2022). https://doi.org/10.1038/s41467-022-32595-4 [doi]

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http://echo.ismrm.org/p/ISMRM2026/465-05-003