Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
464-02-013 ISMRM Abstract

A Large-Format 3D-Printed Diffusion Phantom for Cross-Platform Muscle Microstructure Validation

Primary: Diffusion - Microstructure
Secondary: Musculoskeletal - Muscle
464-02-013 · Validating Diffusion MRI: Reproducibility, Simulations, and Phantoms · Tuesday, 12 May, 9:15 AM–10:10 AM · Digital Posters Row E
Keywords: Skeletal Muscle 3D Printing Diffusion Tensor Imaging (DTI) Phantom study Multi-vendor
Accepted
David B Berry 1, Lin Huang2, Jascha Gaarder1, Yajun Ma3,4,4,5,6, Vitaly Galinsky4, Lawrence R Frank7, Shaochen Chen2, Samuel R Ward1
1Orthopaedic Surgery, University of California, San Diego, United States of America
2Chemical and Nanoengineering, University of California, San Diego, United States of America
3University of California, Berkeley, United States of America
4University of California, San Diego, United States of America
5Department of Radiology, University of California, Berkeley, United States of America
6Department of Radiology, University of California, San Diego, United States of America
7Center for Scientific Computation in Imaging, University of California, San Diego, United States of America
Presenting Author: David B Berry

Synopsis

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References

1. D. B. Berry, J. A. Gordon III, V. Adair, L. R. Frank, and S. R. Ward, “From Voxels to Physiology: A Review of Diffusion Magnetic Resonance Imaging Applications in Skeletal Muscle,” Journal of Magnetic Resonance Imaging, vol. 61, no. 2, pp. 595–615, 2025, doi: 10.1002/jmri.29489. [doi]
2. D. B. Berry, S. You, J. Warner, L. R. Frank, S. Chen, and S. R. Ward, “A 3D Tissue-Printing Approach for Validation of Diffusion Tensor Imaging in Skeletal Muscle,” Tissue Engineering Part A, vol. 23, no. 17–18, pp. 980–988, Sept. 2017, doi: 10.1089/ten.tea.2016.0438. [doi]
3. W. Zhu et al., “Direct 3D bioprinting of prevascularized tissue constructs with complex microarchitecture,” Biomaterials, vol. 124, pp. 106–115, Apr. 2017, doi: 10.1016/j.biomaterials.2017.01.042. [doi]
4. D. B. Berry, E. K. Englund, V. Galinsky, L. R. Frank, and S. R. Ward, “Varying diffusion time to discriminate between simulated skeletal muscle injury models using stimulated echo diffusion tensor imaging,” Magnetic Resonance in Medicine, vol. 85, no. 5, pp. 2524–2536, 2021, doi: 10.1002/mrm.28598. [doi]
5. A. R. McDowell, T. Feiweier, F. Muntoni, M. G. Hall, and C. A. Clark, “Clinically feasible diffusion MRI in muscle: Time dependence and initial findings in Duchenne muscular dystrophy,” Magnetic Resonance in Medicine, vol. 86, no. 6, pp. 3192–3200, 2021, doi: 10.1002/mrm.28945. [doi]
6. D. B. Berry, V. L. Galinsky, E. B. Hutchinson, J. P. Galons, S. R. Ward, and L. R. Frank, “Double pulsed field gradient diffusion MRI to assess skeletal muscle microstructure,” Magnetic Resonance in Medicine, vol. 90, no. 4, pp. 1582–1593, 2023, doi: 10.1002/mrm.29751. [doi]
7. L. R. Frank, B. Zahneisen, and V. L. Galinsky, “JEDI: Joint Estimation Diffusion Imaging of macroscopic and microscopic tissue properties,” Magn Reson Med, vol. 84, no. 2, pp. 966–990, Aug. 2020, doi: 10.1002/mrm.28141. [doi]

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http://echo.ismrm.org/p/ISMRM2026/464-02-013