Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
565-01-012 ISMRM Abstract

Serostatus-Independent Free-Water Fraction in Cervical Spinal WM in NMOSD: Equivalence Analysis with diffusion Standard Model

Primary: Neuro - Spinal Cord
Secondary: Neuro - Multiple Sclerosis
565-01-012 · Neuroinflammation: Fluids and Flow · Wednesday, 13 May, 8:20 AM–9:15 AM · Digital Posters Row F
Keywords: Spinal Cord Diffusion MRI Standard model imaging Spinal Cord Toolbox Neuromyelitis optica spectrum disorder
Accepted
Masaaki Hori1,2, Akifumi Hagiwara3, Takafumi Kitagawa 3, Kouhei Kamiya4, Issei Fukunaga5, Katsutoshi Murata6, Julien Cohen-Adad7,8,9,10, Shigeki Aoki3,11,12, Koji Kamagata3
1Radiology, Toho University, Tokyo, Japan
2Juntendo University Graduate School of Medicine, Tokyo, Japan
3Radiology, Juntendo University Graduate School of Medicine, Tokyo, Japan
4Toho University, Tokyo, Japan
5Juntendo University Faculty of Health Science, Tokyo, Japan
6Siemens Japan K.K., Tokyo, Japan
7NeuroPoly Lab, Montreal, Canada
8Mila - Quebec AI Institute, Montreal, Canada
9Functional Neuroimaging Unit, Montreal, Canada
10Centre de Recherche du CHU Sainte-Justine, Montreal, Canada
11Data Science, Juntendo University Graduate School of Medicine, Tokyo, Japan
12Juntendo University Faculty of Health Data Science, Chiba, Japan
Presenting Author: Takafumi Kitagawa

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References

1. Wingerchuk DM,et al; InternationalPanel for NMO Diagnosis. International consensus diagnostic criteria for neuromyelitis optica spectrum disorders. Neurology. 2015 Jul 14;85(2):177-89. doi: 10.1212/WNL.0000000000001729. [doi]
2. Wu Y, et al. Double-negative neuromyelitis optica spectrum disorder. Mult Scler. 2023 Oct;29(11-12):1353-1362. doi: 10.1177/13524585231199819. [doi]
3. Dmitry S. Novikov, et al. Rotationally-invariant mapping of scalar and orientational metrics of neuronal microstructure with diffusion MRI, NeuroImage, Volume 174, 2018, Pages 518-538. doi: 10.1016/j.neuroimage.2018.03.006. [doi]
4. https://github.com/NYU-DiffusionMRI/SMI
5. De Leener B,et al. SCT: Spinal Cord Toolbox, an open-source software for processing spinal cord MRI data. Neuroimage. 2017 Jan 15;145(Pt A):24-43. doi: 10.1016/j.neuroimage.2016.10.009. [doi]
6. https://github.com/spinalcordtoolbox/spinalcordtoolbox
7. Kato S, et al.Microstructural white matter abnormalities in multiple sclerosis and neuromyelitis optica spectrum disorders: Evaluation by advanced diffusion imaging. J Neurol Sci. 2022 May 15;436:120205. doi: 10.1016/j.jns.2022.120205. [doi]

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http://echo.ismrm.org/p/ISMRM2026/565-01-012