Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
565-04-009 ISMRM Abstract

A Radiomics-Based Nomogram for Predicting Complete Remission to Chemoradiotherapy in Intracranial Germ Cell Tumors

Primary: Neuro - Tumors
Secondary: Analysis Methods - Radiomics
565-04-009 · Neuroradiomics · Wednesday, 13 May, 2:35 PM–3:30 PM · Digital Posters Row F
Keywords: Radiomics Magnetic resonance imaging Intracranial germ cell tumors Complete remission
Accepted
Yaxi Chen 1, Liangping Luo1,2,3, wei cui4
1Medical Imaging Center, The First Affiliated Hospital of Jinan University, Guangzhou, China
2Department of Radiology and Nuclear Medicine, The Fifth Affiliated Hospital of Jinan University (Shenhe People’s Hospital), China
3The Guangzhou Key Laboratory of Molecular and Functional Imaging for Clinical Translation, The First Affiliated Hospital of Jinan University, Guangzhou, China
4MRI Research, GE Healthcare, Beijing, China
Presenting Author: Yaxi Chen

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References

1. [1]S. Liu, L. Ren, X. Gao, M. Hao and G. Wang: Pathogenesis of central nervous system germ cell tumors. Frontiers in Oncology 2022, 12.https://doi.org/10.3389/fonc.2022.991484. [doi]
2. [2]M. Nishimoto, K. Ohara, D. Kamamoto, R. Tamura, T. Miwa, K. Yoshida and H. Sasaki: Tumor immune microenvironment is associated with the growth of intracranial germinomas. J Neurooncol 2020, 146(1):139-146.https://doi.org/10.1007/s11060-019-03355-0. [doi]
3. [3]G. Wang, Y. Jia, Y. Ye, E. Kang, H. Chen, J. Wang and X. He: Clinical and Epidemiological Study of Intracranial Tumors in Children and Identification of Diagnostic Biomarkers for the Most Common Tumor Subtype and Their Relationship with the Immune Microenvironment Through Bioinformatics Analysis. Journal of Molecular Neuroscience 2022, 72(6):1208-1223.https://doi.org/10.1007/s12031-022-02003-z. [doi]
4. [4]H. Shimizu, K. Motomura, F. Ohka, K. Aoki, K. Tanahashi, M. Hirano, L. Chalise, T. Nishikawa, J. Yamaguchi, J. Yoshida, A. Natsume and T. Wakabayashi: Long-term survival in patients with primary intracranial germ cell tumors treated with surgery, platinum-based chemotherapy, and radiotherapy: a single-institution study. Journal of Neurosurgery 2021, 135(2):449-457.https://doi.org/10.3171/2020.6.Jns20638. [doi]
5. [5]S. Cheng, J.-P. Kilday, N. Laperriere, L. Janzen, J. Drake, E. Bouffet and U. Bartels: Outcomes of children with central nervous system germinoma treated with multi-agent chemotherapy followed by reduced radiation. Journal of Neuro-Oncology 2016, 127(1):173-180.https://doi.org/10.1007/s11060-015-2029-1. [doi]
6. [6]A. S. C. Foo, C. Lim, D. Q. Q. Chong, D. Y. H. Tan and C. K. Tham: Primary intracranial germ cell tumours: Experience of a single South-East Asian institution. Journal of Clinical Neuroscience 2014, 21(10):1761-1766.https://doi.org/10.1016/j.jocn.2014.01.021. [doi]
7. [7]N. Kremenevski, M. Buchfelder and N. Hore: Intracranial Germinomas: Diagnosis, Pathogenesis, Clinical Presentation, and Management. Current Oncology Reports 2023, 25(7):765-775.https://doi.org/10.1007/s11912-023-01416-2. [doi]
8. [8]H. Nakamura, H. Takami, T. Yanagisawa, T. Kumabe, T. Fujimaki, Y. Arakawa, K. Karasawa, K. Terashima, H. Yokoo, K. Fukuoka, Y. Sonoda, K. Sakurada, Y. Mineharu, T. Soejima, M. Fujii, N. Shinojima, J. Hara, K. Yamasaki, J. Fujimura, F. Yamasaki, M. Takahashi, T. Suzuki, I. Sato, R. Nishikawa and K. Sugiyama: The Japan Society for Neuro-Oncology guideline on the diagnosis and treatment of central nervous system germ cell tumors. Neuro-Oncology 2022, 24(4):503-515.https://doi.org/10.1093/neuonc/noab242. [doi]
9. [9]J. Wong, K. Goddard, N. Laperriere, J. Dang, E. Bouffet, U. Bartels, D. Hodgson, S. Tyldesley, J. Hukin, S. Cheng, P. L. Bedard and A. C. Lo: Long term toxicity of intracranial germ cell tumor treatment in adolescents and young adults. Journal of Neuro-Oncology 2020, 149(3):523-532.https://doi.org/10.1007/s11060-020-03642-1. [doi]
10. [10]B. Chen, C. Chen, Y. Zhang, Z. Huang, H. Wang, R. Li and J. Xu: Differentiation between Germinoma and Craniopharyngioma Using Radiomics-Based Machine Learning. Journal of Personalized Medicine 2022, 12(1).https://doi.org/10.3390/jpm12010045. [doi]
11. [11]Y. Fan, X. Huo, X. Li, L. Wang and Z. Wu: Non-invasive preoperative imaging differential diagnosis of pineal region tumor: A novel developed and validated multiparametric MRI-based clinicoradiomic model. Radiotherapy and Oncology 2022, 167:277-284.https://doi.org/10.1016/j.radonc.2022.01.005. [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/565-04-009