Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
667-01-011 ISMRM Abstract

Protocol Optimization for IMPULSED-Based ex-vivo Microstructural Assessment Using OGSE and PGSE Simulations

Primary: Diffusion - Microstructure
Secondary: Diffusion - Simulation/Validation
667-01-011 · Innovations in Diffusion MRI: Systems, Sequences, and Protocol Design · Thursday, 14 May, 8:30 AM–9:25 AM · Digital Posters Row H
Keywords: Simulations 7T IMPULSED OGSE diffusion imaging Time-dependent microstructure diffusion MRI
Accepted
Jeroen T.J. de Groot1,2, Carlijn Jamila Guichelaar 2, Chantal Tax3,4, Marielle Philippens2
1Biomedical Engineering, Eindhoven University of Technology, Eindhoven, Netherlands
2Department of Radiotherapy, University Medical Center Utrecht, Utrecht, Netherlands
3Center for Image Sciences, University Medical Center Utrecht, Utrecht, Netherlands
4Cardiff University Brain Research Imaging Centre (CUBRIC), Cardiff University, Cardiff, United Kingdom
Presenting Author: Carlijn Jamila Guichelaar

Synopsis

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References

1. Koh DM, Collins DJ. Diffusion-weighted MRI in the body: applications and challenges in oncology. AJR Am J Roentgenol. 2007 Jun;188(6):1622-35. doi: 10.2214/AJR.06.1403. PMID: 17515386. [doi] [pmid]
2. Schachter M, Does MD, Anderson AW, Gore JC. Measurements of restricted diffusion using an oscillating gradient spin-echo sequence. J Magn Reson. 2000 Dec;147(2):232-7. doi: 10.1006/jmre.2000.2203. PMID: 11097814. [doi] [pmid]
3. Jiang X, Li H, Xie J, McKinley ET, Zhao P, Gore JC, Xu J. In vivo imaging of cancer cell size and cellularity using temporal diffusion spectroscopy. Magn Reson Med. 2017 Jul;78(1):156-164. doi: 10.1002/mrm.26356. Epub 2016 Aug 6. PMID: 27495144; PMCID: PMC5293685. [doi] [pmid]
4. Michael, Eric Seth; Hennel, Franciszek; Pruessmann, Klaas Paul. Evaluating diffusion dispersion across an extended range of b-values and frequencies: Exploiting gap-filled OGSE shapes, strong gradients, and spiral readouts. Magnetic Resonance in Medicine, 87(6):2710–2723, 2022. https://doi.org/10.1002/mrm.29161 [doi]
5. Junzhong Xu, Sean P. Devan, Diwei Shi, Adithya Pamulaparthi, Nicholas Yan, Zhongliang Zu, David S. Smith, Kevin D. Harkins, John C. Gore, Xiaoyu Jiang. MATI: A GPU-accelerated toolbox for microstructural diffusion MRI simulation and data fitting with a graphical user interface. Magnetic Resonance Imaging, 122:110428, 2025. https://doi.org/10.1016/j.mri.2025.110428 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/667-01-011