Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
505-03-009 ISMRM Abstract

In Vivo Conductivity Tensor MRI Reveals Ionic Microenvironment Alterations in Alzheimer’s Disease

Primary: Contrast Mechanisms - Electromagnetic Tissue Properties
Secondary: Neuro - Alzheimer's Disease
505-03-009 · Teasing Out the Microstructure of the Brain and Nervous System · Wednesday, 13 May, 1:40 PM–3:30 PM · Ballroom West
Keywords: Alzheimer's Disease Electromagnetic Tissue Properties Electrical Conductivity Conductivity Tensor Imaging Neurodegeneration Biomarker
Accepted
Nitish Katoch 1, Jinwoo Hwang1, Eunju Kim1, Geon-Ho Jahng2
1Clinical Science, Philips Korea, Seoul, Korea, Republic of
2Department of Radiology, Kyung Hee University Hospital at Gangdong, College of Medicine, Kyung Hee University, Seoul, Korea, Republic of
Presenting Author: Nitish Katoch

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References

1. Park S. “Application of high-frequency conductivity map using MRI to evaluate the brain of Alzheimer’s disease patients.” Front Neurol. 13: 872878 (2022). (https://doi.org/10.3389/fneur.2022.872878) [doi]
2. Chu J. “Brain tissue electrical conductivity as a promising biomarker for dementia assessment using MRI.” Alzheimers Dement. 21(6): e70270 (2025). (https://doi.org/10.1002/alz.70270) [doi]
3. Katoch N. “Conductivity tensor imaging of in-vivo human brain and experimental validation using giant vesicle suspension”. IEEE TMI 38, 1569-1577 (2019). (https://doi.org/10.1109/TMI.2018.2884440) [doi]
4. Jahng GH. “Low-frequency dominant electrical conductivity imaging of in vivo human brain using high-frequency conductivity at Larmor frequency and spherical mean diffusivity without external injection current.” Neuroimage. 225: 117466 (2021). (https://doi.org/10.1016/j.neuroimage.2020.117466) [doi]
5. Kaden E. “Multi-compartment microscopic diffusion imaging.” NeuroImage. 139: 346–359 (2016). (https://doi.org/10.1016/j.neuroimage.2016.06.002) [doi]
6. Ding F. “Dysregulation of extracellular potassium distinguishes healthy ageing from neurodegeneration.” Brain. 147(5): 1726–1739 (2024). (https://doi.org/10.1093/brain/awae075) [doi]
7. Bhoi R. “Role of ion channels in Alzheimer’s disease pathophysiology.” J Membrane Biol. 258: 187–212 (2025). (https://doi.org/10.1007/s00232-025-00341-8) [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/505-03-009