Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
362-04-008 ISMRM Abstract

Algorithmic Determination of Early Scan Stopping for GABA-edited MRS

Primary: Contrast Mechanisms - Spectroscopy
Secondary: Acquisition & Reconstruction - Spectroscopy and spectroscopic imaging
362-04-008 · Spectroscopy and Spectroscopic Imaging: Neuro I · Monday, 11 May, 2:45 PM–3:40 PM · Digital Posters Row C
Keywords: Single voxel spectroscopy Scan time reduction In vivo proton magnetic resonance spectroscopy Gamma-aminobutyric acid Edited magnetic resonance spectroscopy
Accepted
Hanna Bugler 1,2,3, Roberto Souza2,4, Ashley D Harris 2,5,6
1Biomedical Engineering, University of Calgary, Calgary, Canada
2Hotchkiss Brain Institute, University of Calgary, Calgary, Canada
3Alberta Children's Hospital Research Insitute, Calgary, Canada
4Electrical and Software Engineering, University of Calgary, Calgary, Canada
5Department of Radiology, University of Calgary, Calgary, Canada
6Alberta Children's Hospital Research Institute, University of Calgary, Calgary, Canada
Presenting Author: Hanna Bugler

Synopsis

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References

1. Mullins PG, McGonigle DJ, O’Gorman RL, et al. Current practice in the use of MEGA-PRESS spectroscopy for the detection of GABA. NeuroImage. 2014; 86:43-52. doi: 10.1016/j.neuroimage.2012.12.004. [doi]
2. Peek AL, Rebbeck TJ, Leaver AM et al. A comprehensive guide to MEGA-PRESS for GABA measurement. Anal Biochem. 2023;669(15):115113. doi:10.1016/j.ab.2023.115113. [doi]
3. Mikkelsen M, Loo RS, Puts NAJ, Edden RAE, Harris AD. Designing GABA-edited magnetic resonance spectroscopy studies: Considerations of scan duration, signal-to-noise ratio and sample size. J Neurosci Methods. 2018; 303:86-94. doi: 10.1016/j.jneumeth.2018.02.012. [doi]
4. Andronesi OC, Bhattacharyya PK, Bogner W et al. Motion correction methods for MRS: expert’s consensus recommendations. NMR Biomed. 2021;34(5): e4364. doi: 10.1002/nbm.4364. [doi]
5. Choi IY, Andronesi OC, Barker PB et al. Spectral Editing in 1H Magnetic Resonance Spectroscopy: Expert’s Consensus Recommendations. NMR Biomed. 2020;34(5): e4411. doi:10.1002/nbm.4411. [doi]
6. Wilson M, Andronesi O, Barker PB et al. Methodological consensus on clinical proton MRS of the brain: Review and recommendations. Magn Reson Med. 2019;82(2):527-550. doi:10.1002/mrm.27742. [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/362-04-008