Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
467-04-008 ISMRM Abstract

Respiratory and Cardiac Self-navigated Free-Breathing Fatty Acid Composition MRI of Human Epicardial Adipose Tissue

Primary: Cardiovascular - Heart Failure
Secondary: Contrast Mechanisms - Fat & Fat/Water Separation
467-04-008 · Cardiovascular Imaging and Motion Correction Strategies · Tuesday, 12 May, 2:35 PM–3:30 PM · Digital Posters Row H
Keywords: Fat-water MR quantification Radial cardiac MRI Self-navigation Fatty acid composition Motion-resolved MRI
Accepted
Anshul Pundhir1, John T Echols2, Thomas P Skacel 1, Shuo Wang3, Amit R Patel3, Frederick H Epstein1
1Department of Biomedical Engineering, University of Virginia, Charlottesville, United States of America
2Department of Electrical and Computer Engineering, University of Virginia, Charlottesville, United States of America
3Division of Cardiovascular Medicine, University of Virginia, Charlottesville, United States of America
Presenting Author: Thomas P Skacel

Synopsis

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References

1. Cikim, A. S. et al. Epicardial adipose tissue, hepatic steatosis and obesity. Journal of endocrinological investigation 30, 459–464 (2007).
2. Iacobellis, G., Malavazos, A. E. & Corsi, M. M. Epicardial fat: from the biomolecular aspects to the clinical practice. The international journal of biochemistry & cell biology 43, 1651–1654 (2011).
3. Walker, M. E. et al. Dietary patterns influence epicardial adipose tissue fatty acid composition and inflammatory gene expression in the Ossabaw pig. The Journal of Nutritional Biochemistry 70, 138–146 (2019).
4. Vaittinen, M. et al. Interorgan cross talk between fatty acid metabolism, tissue inflammation, and FADS2 genotype in humans with obesity. Obesity 25, 545–552 (2017).
5. Echols, J. T., Wang, S., Patel, A. R., Hogwood, A. C., Abbate, A., & Epstein, F. H. (2025). Fatty acid composition MRI of epicardial adipose tissue: Methods and detection of proinflammatory biomarkers in ST‐segment elevation myocardial infarction patients. Magnetic Resonance in Medicine, 93(2), 519-535.
6. Echols, J., Shah, S., & Epstein, F. (2022). Fatty acid composition MRI of human epicardial adipose tissue. Proc 31st ISMRM, 1745.
7. Berglund, J., Ahlström, H. & Kullberg, J. Model‐based mapping of fat unsaturation and chain length by chemical shift imaging—phantom validation and in vivo feasibility. Magnetic Resonance in Medicine 68,1815–1827 (2012).
8. Hodson L, Skeaff CM, Fielding BA. Fatty acid composition of adipose tissue and blood in humans and its use as a biomarker of dietary intake. Progress in Lipid Research. 47, 348-380 (2008).
9. United States Department of Agriculture. (2019). FoodData Central. U.S. Department of Agriculture, Agricultural Research Service. Retrieved from https://fdc.nal.usda.gov

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/467-04-008