Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
465-04-012 ISMRM Abstract

Edge-Centric Functional Connectivity and ALFF Reveal Dual-Track Network Alterations Across Different Cognitive States in PD

Primary: Neuro - Parkinson's Disease
Secondary: Brain Function and fMRI - Functional Connectivity
465-04-012 · Image Analysis for Alzheimer's and Parkinson's · Tuesday, 12 May, 2:35 PM–3:30 PM · Digital Posters Row F
Keywords: Parkinson's Disease Mild cognitive impairment Amplitude of low-frequency fluctuations Resting-state functional MRI Edge-centric functional connectivity
Accepted
Boyu Chen 1, Yueluan Jiang2, Fangxiao Cheng3
1Radiology, The First Hospital of China Medical University, Shenyang, China
2MR Research Collaboration Team, Siemens Healthineers Ltd., Beijing, China
3Institute of Medical Technology, Peking University Health Science Center, Beijing, China
Presenting Author: Boyu Chen

Synopsis

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References

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3. Yang B, Wang X, Mo J, Li Z, Hu W, Zhang C, Zhao B, Gao D, Zhang X, Zou L, Zhao X, Guo Z, Zhang J, Zhang K. The altered spontaneous neural activity in patients with Parkinson's disease and its predictive value for the motor improvement of deep brain stimulation. Neuroimage Clin. 2023;38:103430. doi: 10.1016/j.nicl.2023.103430. Epub 2023 May 9. PMID: 37182459; PMCID: PMC10197096. [doi] [pmid]
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5. Jo Y, Zamani Esfahlani F, Faskowitz J, Chumin EJ, Sporns O, Betzel RF. The diversity and multiplexity of edge communities within and between brain systems. Cell Rep. 2021 Nov 16;37(7):110032. doi: 10.1016/j.celrep.2021.110032. PMID: 34788617. [doi] [pmid]
6. Shang S, Zhu S, Wu J, Xu Y, Chen L, Dou W, Yin X, Chen YC, Shen D, Ye J. Topological disruption of high-order functional networks in cognitively preserved Parkinson's disease. CNS Neurosci Ther. 2023 Feb;29(2):566-576. doi: 10.1111/cns.14037. Epub 2022 Dec 5. PMID: 36468414; PMCID: PMC9873517. [doi] [pmid]
7. Fiorenzato E, Moaveninejad S, Weis L, Biundo R, Antonini A, Porcaro C. Brain Dynamics Complexity as a Signature of Cognitive Decline in Parkinson's Disease. Mov Disord. 2024 Feb;39(2):305-317. doi: 10.1002/mds.29678. Epub 2023 Dec 6. PMID: 38054573. [doi] [pmid]

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http://echo.ismrm.org/p/ISMRM2026/465-04-012