Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
562-02-003 ISMRM Abstract

Intratumoral Heterogeneity of DCE-MRI for Predicting Pathological Response to Neoadjuvant Chemotherapy in Breast Cancer

Accepted
Wenjie Jiang 1, Chen Bai1, Xueying Zhao2, Xinwei Tang1, Xingke Huang1, Xiaoying Li1, Xiang Zhang1, jun shen1
1Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University,, Guangzhou, China
2MR Research, GE HealthCare, Beijing, China
Presenting Author: Wenjie Jiang

Synopsis

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References

1. Korde LA, Somerfield MR, Carey LA, et al. Neoadjuvant Chemotherapy, Endocrine Therapy, and Targeted Therapy for Breast Cancer: ASCO Guideline. J Clin Oncol. 2021 May 1;39(13):1485-1505. doi: 10.1200/JCO.20.03399. Epub 2021 Jan 28. PMID: 33507815; PMCID: PMC8274745. [doi] [pmid]
2. I-SPY2 Trial Consortium; Yee D, DeMichele AM, Yau C, et al. Association of Event-Free and Distant Recurrence-Free Survival With Individual-Level Pathologic Complete Response in Neoadjuvant Treatment of Stages 2 and 3 Breast Cancer: Three-Year Follow-up Analysis for the I-SPY2 Adaptively Randomized Clinical Trial. JAMA Oncol. 2020 Sep 1;6(9):1355-1362. doi: 10.1001/jamaoncol.2020.2535. PMID: 32701140; PMCID: PMC7378873. [doi] [pmid]
3. Shi Z, Huang X, Cheng Z, et al. MRI-based Quantification of Intratumoral Heterogeneity for Predicting Treatment Response to Neoadjuvant Chemotherapy in Breast Cancer. Radiology. 2023 Jul;308(1):e222830. doi: 10.1148/radiol.222830. Erratum in: Radiology. 2023 Jul;308(1):e239021. doi: 10.1148/radiol.239021. PMID: 37432083. [doi] [pmid]
4. McDonald KA, Kawaguchi T, Qi Q, et al. Tumor Heterogeneity Correlates with Less Immune Response and Worse Survival in Breast Cancer Patients. Ann Surg Oncol. 2019 Jul;26(7):2191-2199. doi: 10.1245/s10434-019-07338-3. Epub 2019 Apr 8. PMID: 30963401; PMCID: PMC6545241. [doi] [pmid]

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