Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
363-04-010 ISMRM Abstract

Sub-voxel Quantitative Susceptibility Mapping Differentiates Paramagnetic and Diamagnetic Alterations in PD and PD mimics

Primary: Neuro - Parkinson's Disease
Secondary: Acquisition & Reconstruction - Open source software, sequences, and reconstruction algorithms
363-04-010 · From Iron to Intelligence: Quantitative Imaging and AI in Brain Disorders · Monday, 11 May, 2:45 PM–3:40 PM · Digital Posters Row D
Keywords: Parkinson's Disease Quantitative Susceptibility Mapping (QSM) Paramagnetic susceptibility Diamagnetic susceptibility PD mimics
Accepted
Peng Liu1, Junye Yao 2, Naying He3, Fuhua Yan4,5
1Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
2Clinical & Technical Support, Philips Healthcare, Guangzhou, China
3Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
4Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China
5College of Health Science and Technology, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Presenting Author: Junye Yao

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References

1. Li Z, Feng R, Liu Q, et al. APART-QSM : An improved sub-voxel quantitative susceptibility mapping for susceptibility source separation using an iterative data fitting method. Neuroimage. 2023;274:120148. doi:10.1016/j.neuroimage.2023.120148 [doi]
2. Lao G, Liu Q, Li Z, Guan X, Xu X, Zhang Y, Wei H. Sub-voxel quantitative susceptibility mapping for assessing whole-brain magnetic susceptibility from ages 4 to 80. Hum Brain Mapp. 2023 Dec 1;44(17):5953-5971. doi: 10.1002/hbm.26487. [doi]
3. Jin Z, Wang Y, Jokar M, Li Y, Cheng Z, Liu Y, Tang R, Shi X, Zhang Y, Min J, Liu F, He N, Yan F, Haacke EM. Automatic detection of neuromelanin and iron in the midbrain nuclei using a magnetic resonance imaging-based brain template. Hum Brain Mapp. 2022 Apr 15;43(6):2011-2025. doi: 10.1002/hbm.25770. [doi]
4. Dexter DT, Jenner P, Schapira AH, Marsden CD. Alterations in levels of iron, ferritin, and 4. Dexter DT, Jenner P, Schapira AH, Marsden CD. Alterations in levels of iron, ferritin, and other trace metals in neurodegenerative diseases affecting the basal ganglia. The Royal Kings and Queens Parkinson's Disease Research Group. Ann Neurol. 1992;32 Suppl:S94-100. doi: 10.1002/ana.410320716. [doi]
5. Mohammadi S, Ghaderi S. Parkinson’s disease and Parkinsonism syndromes: Evaluating iron deposition in the putamen using magnetic susceptibility MRI techniques - A systematic review and literature analysis. Heliyon. 2024;10(7). doi:10.1016/j.heliyon.2024.e27950 [doi]
6. Nikparast F, Ganji Z, Danesh Doust M, Faraji R, Zare H. Brain pathological changes during neurodegenerative diseases and their identification methods: How does QSM perform in detecting this process? Insights Imaging. 2022 Apr 13;13(1):74. doi: 10.1186/s13244-022-01207-6. [doi]

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http://echo.ismrm.org/p/ISMRM2026/363-04-010