Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
551-02-004 / 551-02-004 ISMRM Abstract

The Development of a Novel DiaCEST Platform with Highly Shifted Exchanging Proton

Primary: Contrast Mechanisms - CEST / APT / NOE
Secondary: Preclinical Animal & in vitro MR - Probes & Targets
551-02-004 · MRI of Renal Function · Wednesday, 13 May, 1:40 PM–3:16 PM · Power Pitch Theatre 1
551-02-004 · MRI of Renal Function · Wednesday, 13 May, 1:40 PM–3:16 PM · Power Pitch Theatre 1
Keywords: CEST MRI 3T Highly shifted exchanging proton DiaCEST agent
Accepted
Mai Huynh 1, Sara Chirayil1, Janaka Wansapura1, Elena Vinogradov2, Xiaodong Wen1, Mariangela Boccalon3, Emily Buchanan1, Zsolt Baranyai3, Zoltan Kovacs1,4
1Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, United States of America
2Department of Radiology, University of Texas Southwestern Medical Center, Dallas, United States of America
3Bracco Imaging Spa, Bracco Imaging Spa, Bracco Imaging - CRB Trieste, Trieste, Italy
4Department of Chemistry and Biochemistry, University of Texas at Dallas, Richardson, United States of America
Presenting Author: Mai Huynh

Synopsis

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References

1. Vinogradov E, et al. CEST: From basic principles to applications, challenges and opportunities. J Magn Reson. 2013; 229:155-172.
2. Viswanathan S, et al. Alternatives to Gadolinium-Based Metal Chelates for Magnetic Resonance Imaging. Chem Rev. 2010; 110(5):2960-3018.
3. Freeman R, Morris, GA. The ‘DANTE’ experiment. J Magn Reson. 2011; 213:244-246.
4. Yang X, et al. Salicylic Acid and Analogues as diaCEST MRI Contrast Agents with Highly Shifted Exchangeable Proton Frequencies. Angew Chem Int Ed Engl. 2013; 52(31):8116-8119.

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/551-02-004