Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
304-03-002 ISMRM Abstract

Vessel Architecture Imaging enables Quantitative Differentiation of Glioblastoma and Brain Metastasis

Primary: Contrast Mechanisms - Perfusion
Secondary: Body - Vessels
304-03-002 · Precision MRI: Advanced Quantitative Imaging and Biomarkers for Brain Tumors · Monday, 11 May, 1:50 PM–3:40 PM · Ballroom East
Keywords: Vessels Metastasis MRI High-Grade Glioma Brain Tumor classification
Accepted
Dongnan Zhao 1,2,3, Wanxin Dong1,2, Jin Fang4, ke zhang5, Shiji Li1,2, Jingfei Li1,2,6, Guihua Jiang4, Chen Chen7, Ye Li1,2, Zhanli Hu2,8, Xin Liu1,2, Dong Liang2,8, Hairong Zheng1,2, Na Zhang1,2
1Paul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China
2State Key Laboratory of Biomedical Imaging Science and System, Shenzhen, China
3NanjingUniversity School of Modern Engineering andApplied sciences, Nanjing, China
4Guangdong Second People's Hospital, Guangzhou, China
5Department of Diagnostic and Interventional Radiology, Heidelberg University Hospital, Heidelberg, Germany
6College of Information Science and Engineering, Northeastern University, Shenyang, China
7Shanghai United Imaging Healthcare Co., Ltd, Shanghai, China
8Research Center for Medical AI, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China
Presenting Author: Dongnan Zhao

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References

1. Wu C X, Lin G S, Lin Z X, et al. Peritumoral edema shown by MRI predicts poor clinical outcome in glioblastoma [J]. World J Surg Oncol, 2015, 13: 97.doi：10.1186/s12957-015-0496-7
2. Lemercier P, Paz Maya S, Patrie J T, et al. Gradient of apparent diffusion coefficient values in peritumoral edema helps in differentiation of glioblastoma from solitary metastatic lesions [J]. AJR Am J Roentgenol, 2014, 203(1): 163-9.doi：10.2214/AJR.13.11186
3. Aparici-Robles F, Davidhi A, Carot-Sierra J M, et al. Glioblastoma versus solitary brain metastasis: MRI differentiation using the edema perfusion gradient [J]. J Neuroimaging, 2022, 32(1): 127-33.doi： https://doi.org/10.1111/jon.12920 [doi]
4. Bauer A H, Erly W, Moser F G, et al. Differentiation of solitary brain metastasis from glioblastoma multiforme: a predictive multiparametric approach using combined MR diffusion and perfusion [J]. Neuroradiology, 2015, 57(7): 697-703.doi：https://doi.org/10.1007/s00234-015-1524-6 [doi]
5. Zhang K, Yun S D, Triphan S M F, et al. Vessel architecture imaging using multiband gradient-echo/spin-echo EPI [J]. PLoS One, 2019, 14(8): e0220939.doi：https://doi.org/10.1371/journal.pone.0220939 [doi]
6. Kiselev V G, Strecker R, Ziyeh S, et al. Vessel size imaging in humans [J]. Magnetic Resonance in Medicine: An Official Journal of the International Society for Magnetic Resonance in Medicine, 2005, 53(3): 553-63.doi：https://doi.org/10.1002/mrm.20383 [doi]
7. Kellner E, Breyer T, Gall P, et al. MR evaluation of vessel size imaging of human gliomas: Validation by histopathology [J]. Journal of Magnetic Resonance Imaging, 2015, 42(4): 1117-25.doi：https://doi.org/10.1002/jmri.24864 [doi]
8. Hsu Y Y, Yang W S, Lim K E, et al. Vessel size imaging using dual contrast agent injections [J]. J Magn Reson Imaging, 2009, 30(5): 1078-84.doi：https://doi.org/10.1002/jmri.21960 [doi]

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http://echo.ismrm.org/p/ISMRM2026/304-03-002