Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
662-01-012 ISMRM Abstract

Towards the assessment of mesial temporal lobe epilepsy with elastography and perfusion MRI at 7T

Primary: Neuro - Epilepsy
Secondary: Contrast Mechanisms - Elastography
662-01-012 · Advanced Quantitative and Diffusion MRI for Epilepsy: From Lesion Detection to Clinical Translation · Thursday, 14 May, 8:30 AM–9:25 AM · Digital Posters Row C
Keywords: Arterial spin labelling Epilepsy MR elastography Ultra-high-field Multimodal neuroimaging
Accepted
Caitlin M Neher 1, Oleksandr Khegai2, Lara V Marcuse3, Madeline C Fields3, Mehmet Kurt1, Priti Balchandani4
1Mechanical Engineering, University of Washington, Seattle, United States of America
2Helen Wills Neuroscience Institute, University of California, Berkeley, United States of America
3Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, United States of America
4BioMedical Engineering and Imaging Institute (BMEII), Icahn School of Medicine at Mount Sinai, New York, United States of America
Presenting Author: Caitlin M Neher

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References

1. Kuzniecky, R., Burgard, S., Faught, E., Morawetz, R., & Bartolucci, A. (1993). Predictive value of magnetic resonance imaging in temporal lobe epilepsy surgery. Archives of neurology, 50(1), 65–69. https://doi.org/10.1001/archneur.1993.00540010059018 [doi]
2. Fallah, A., Subramaniam, T., Phillips, H.W. et al. Novel tonometer device distinguishes brain stiffness in epilepsy surgery. Sci Rep 10, 20978 (2020). https://doi.org/10.1038/s41598-020-77888-0 [doi]
3. Huesmann GR, Schwarb H, Smith DR, Pohlig RT, Anderson AT, McGarry MDJ, Paulsen KD, Wszalek TM, Sutton BP, Johnson CL. Hippocampal stiffness in mesial temporal lobe epilepsy measured with MR elastography: Preliminary comparison with healthy participants. Neuroimage Clin. 2020;27:102313. doi: 10.1016/j.nicl.2020.102313. Epub 2020 Jun 16. PMID: 32585569; PMCID: PMC7322100. [doi] [pmid]
4. Patel DC, Tewari BP, Chaunsali L, Sontheimer H. Neuron-glia interactions in the pathophysiology of epilepsy. Nat Rev Neurosci. 2019 May;20(5):282-297. doi: 10.1038/s41583-019-0126-4. PMID: 30792501; PMCID: PMC8558781. [doi] [pmid]
5. Rentzeperis F, Abdennadher M, Snyder K, Dembny K, Abdollahi S, Zaghloul KA, Talagala L, Theodore WH, Inati SK. Lateralization of interictal temporal lobe hypoperfusion in lesional and non-lesional temporal lobe epilepsy using arterial spin labeling MRI. Epilepsy Res. 2023 Jul;193:107163. doi: 10.1016/j.eplepsyres.2023.107163. Epub 2023 May 9. PMID: 37187039; PMCID: PMC10247543. [doi] [pmid]
6. Triolo, E., Khegai, O., McGarry, M., Lam, T., Veraart, J., Alipour, A., Balchandani, P., & Kurt, M. (2024). Characterizing brain mechanics through 7 tesla magnetic resonance elastography. Physics in medicine and biology, 69(20), 10.1088/1361-6560/ad7fc9. https://doi.org/10.1088/1361-6560/ad7fc9 [doi]
7. McGarry, M. D., Van Houten, E. E., Perriñez, P. R., Pattison, A. J., Weaver, J. B., & Paulsen, K. D. (2011). An octahedral shear strain-based measure of SNR for 3D MR elastography. Physics in medicine and biology, 56(13), N153–N164. https://doi.org/10.1088/0031-9155/56/13/N02 [doi]
8. Neher, C. M., Triolo, E., RezayAraghi, F., Khegai, O., Balchandani, P., McGarry, M., & Kurt, M. (2025). Perfusion-mechanics coupling of the hippocampus. Interface focus, 15(1), 20240051. https://doi.org/10.1098/rsfs.2024.0051 [doi]
9. Jenkinson, M., Beckmann, C. F., Behrens, T. E. J., Woolrich, M. W., & Smith, S. M. (2012). FSL. NeuroImage, 62(2), 782–790. https://doi.org/10.1016/j.neuroimage.2011.09.015 [doi]
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http://echo.ismrm.org/p/ISMRM2026/662-01-012