Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
362-05-004 ISMRM Abstract

Cystathionine-Targeted MRS Study: Cystathionine as an Imaging Biomarker for IDH-Mutant Gliomas With 1p/19q Codeletion

Primary: Neuro - Tumors
Secondary: Physics & Engineering - RF Pulse Design & Fields
362-05-004 · Spectroscopy and Spectroscopic Imaging: Neuro II · Monday, 11 May, 4:10 PM–5:05 PM · Digital Posters Row C
Keywords: Diagnosis/Prediction Cystathionine 1p 19q codeleted glioma Cystathionine-Targeted MRS
Accepted
Xiaozhu Hao 1, Siyuan Fang2, Yefeng Yao2, Zhenwei Yao1
1Huashan Hospital, Fudan University, China
2Shanghai Key Laboratory of Magnetic Resonance, Shanghai, China
Presenting Author: Xiaozhu Hao

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References

1. Cairncross JG, Ueki K, Zlatescu MC, et al. Specific genetic predictors of chemotherapeutic response and survival in patients with anaplastic oligodendrogliomas. J Natl Cancer Inst 1998;90(19):1473–1479. PMID: 9776413. [pmid]
2. Eckel-Passow JE, Lachance DH, Molinaro AM, et al. Glioma groups based on 1p/19q, IDH, and TERT promoter mutations in tumors. N Engl J Med 2015;372(26):2499–2508. PMID: 26061753. [pmid]
3. Patel SH, Poisson LM, Brat DJ, et al. T2-FLAIR mismatch, an imaging biomarker for IDH and 1p/19q status in lower-grade gliomas: a TCGA/TCIA project. Clin Cancer Res 2017;23(20):6078–6085. PMID: 28751449. [pmid]
4. Francesca Branzoli, Clément Pontoizeau, Lucien Tchara, et al. Cystathionine as a marker for 1p/19q codeleted gliomas by in vivo magnetic resonance spectroscopy. Neuro-Oncology 2019; 21(6): 765–774. PMID: 30726924. [pmid]
5. Francesca Branzoli, Roberto Liserre, Dinesh K. Deelchand, et al. Neurochemical Differences between 1p/19q Codeleted and Noncodeleted IDH-mutant Gliomas by in Vivo MR Spectroscopy. Radiology 2023; 308(3):e223255. PMID: 37668523. [pmid]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/362-05-004