562-06-001 ISMRM Abstract

GOing Beyond Activation: Gene Ontology Terms for Functional Interpretation of fMRI Data

Primary: Analysis Methods - Data Processing

Secondary: Brain Function and fMRI - fMRI Analysis

562-06-001 · fMRI: Preclinical · Wednesday, 13 May, 4:55 PM–5:50 PM · Digital Posters Row C

Keywords: Gene expression analysis Allen mouse brain atlas Gene set enrichment analysis GSEA Relative cerebral blood volume (rCBV)

Accepted

Isabel Wank¹, Anja Amthor¹, Christian P Müller², Andreas Hess ^1,3,4

¹Institute of Experimental and Clinical Pharmacology and Toxicology, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany

²Department of Psychiatry and Psychotherapy, University Clinic, Friedrich-Alexander-University of Erlangen-Nürnberg, Erlangen, Germany

³Institute of Neuroradiology, University Hospital Erlangen, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany

⁴FAU NeW – Research Center for New Bioactive Compounds, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany

Presenting Author: Andreas Hess

Synopsis

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References

1. Wank I., Amthor A., Kreitz S., Häfele M., and Hess A. „Gene expression patterns decompose fMRI activation in a sub-region-specific manner in mice after nociceptive stimulation”, NeuroImage, 2025 https://doi.org/10.1016/j.neuroimage.2025.121425 [doi]

2. Wank, I., C. Mittmann, S. Kreitz, D. Chestnykh, C. Mühle, J. Kornhuber, A. Ludwig, L. S. Kalinichenko, C. P. Müller, A Hess. „Neutral sphingomyelinase controls acute and chronic alcohol effects on brain activity.” Neuropharmacology, 2024 https://doi.org/10.1016/j.neuropharm.2024.109948 [doi]

3. Kalinichenko, L. S., et al. "Neutral sphingomyelinase mediates the co-morbidity trias of alcohol abuse, major depression and bone defects." Molecular psychiatry, 2021 https://doi.org/10.1038/s41380-021-01304-w [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/562-06-001