Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
564-05-008 ISMRM Abstract

Towards 7 Tesla whole-brain 3D Dynamic Glucose-Enhanced Imaging with semi-quantitative R1ρ mapping

Primary: Contrast Mechanisms - CEST / APT / NOE
Secondary: Acquisition & Reconstruction - Quantitative Imaging: relaxometry, multi-parametric, MR Fingerprinting, and synthetic MRI
564-05-008 · The qMRI Variety Show: A Little Bit of Everything · Wednesday, 13 May, 4:00 PM–4:55 PM · Digital Posters Row E
Keywords: 7T Spin-Lock GluCEST Whole-brain R1rho
Accepted
Oscar Andersson Forsman 1,2, Daniel Papp3, Carolin Lange1,2, Patrick Liebig4, Henrik Sjöström1,5, Caroline Ingre1,2, Tobias Granberg1,2
1Karolinska Institutet, Solna, Sweden
2Karolinska University Hospital, Stockholm, Sweden
3Siemens Healthineers AB, Stockholm, Sweden
4Siemens Healthineers AG, Forchheim, Germany
5Center for Neurology, Academic Specialist Center, Stockholm, Sweden
Presenting Author: Oscar Andersson Forsman

Synopsis

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References

1. 1, Xu X, Yadav NN, Knutsson L, et al. Dynamic Glucose-Enhanced (DGE) MRI: Translation to Human Scanning and First Results in Glioma Patients. Tomography. 2015;1(2):105-114. doi:10.18383/j.tom.2015.00175 [doi]
2. 2, Knutsson L, Seidemo A, Scherman AR, et al. Arterial Input Functions and Tissue Response Curves in Dynamic Glucose-Enhanced (DGE) Imaging: Comparison between glucoCEST and Blood Glucose Sampling in Humans. Tomography. 2018;4(4):164-171. doi:10.18383/j.tom.2018.00025 [doi]
3. 3, Schuenke P, Koehler C, Korzowski A, et al. Adiabatically prepared spin-lock approach for T1ρ-based dynamic glucose enhanced MRI at ultrahigh fields. Magnetic Resonance in Medicine. 2017;78(1):215-225. doi:10.1002/mrm.26370 [doi]
4. 4, Paech D, Schuenke P, Koehler C, et al. T1ρ-weighted Dynamic Glucose-enhanced MR Imaging in the Human Brain. Radiology. 2017;285(3):914-922. doi:10.1148/radiol.2017162351 [doi]
5. 5 Boyd PS, Breitling J, Zimmermann F, et al. Dynamic glucose-enhanced (DGE) MRI in the human brain at 7 T with reduced motion-induced artifacts based on quantitative R1ρ mapping. Magnetic Resonance in Medicine. 2020;84(1):182-191. doi:10.1002/mrm.28112 [doi]
6. 6 Dickie BR, Jin T, Wang P, et al. Quantitative kinetic modelling and mapping of cerebral glucose transport and metabolism using glucoCESL MRI. J Cereb Blood Flow Metab. 2022;42(11):2066-2079. doi:10.1177/0271678X221108841 [doi]
7. 7 Boehm-Sturm P, Schuenke P, Foddis M, et al. 2-deoxy-D-glucose chemical exchange-sensitive spin-lock MRI of cerebral glucose metabolism after transient focal stroke in the rat. J Cereb Blood Flow Metab. Published online July 8, 2025:0271678X251355049. doi:10.1177/0271678X251355049 [doi]
8. 8 Zaiss, M., Ehses, P. & Scheffler, K. Snapshot-CEST: Optimizing spiral-centric-reordered gradient echo acquisition for fast and robust 3D CEST MRI at 9.4 T. NMR in Biomedicine 31, e3879 (2018). doi: 10.1002/nbm.3879 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/564-05-008