Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
551-03-004 / 551-03-004 ISMRM Abstract

Non-invasive MRI of choroid plexus vascular function

Primary: Neuro - Neurofluids
Secondary: Neuro - Blood Vessels
551-03-004 · Advanced MRI Biomarkers of Brain Aging, Vascular Health, and Alzheimer’s Disease · Wednesday, 13 May, 4:00 PM–5:36 PM · Power Pitch Theatre 1
551-03-004 · Advanced MRI Biomarkers of Brain Aging, Vascular Health, and Alzheimer’s Disease · Wednesday, 13 May, 4:00 PM–5:36 PM · Power Pitch Theatre 1
Keywords: Aging Functional magnetic resonance imaging Choroid plexus Vascular elasticity
Accepted
Peiying Liu 1, Lori Donaldson1, Beini Hu1, Gagan S Wig2,3, Hanzhang Lu4
1Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, United States of America
2Center for Vital Longevity, University of Texas at Dallas, Richardson, United States of America
3Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, United States of America
4Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, United States of America
Presenting Author: Peiying Liu

Synopsis

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References

1. Ghersi-Egea JF, Strazielle N, Catala M, et al. Molecular anatomy and functions of the choroidal blood-cerebrospinal fluid barrier in health and disease. Acta Neuropathol. 2018;135(3):337–361. doi: 10.1007/s00401-018-1807-1. [doi]
2. Iliff JJ, Wang M, Liao Y, et al. A paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid β. Sci Transl Med. 2012;4(147):147ra111. doi: 10.1126/scitranslmed.3003748. [doi]
3. Masseguin C, LePanse S, Corman B, et al. Aging affects choroidal proteins involved in CSF production in Sprague-Dawley rats. Neurobiol Aging. 2005;26(6):917-27. doi: 10.1016/j.neurobiolaging.2004.07.013. [doi]
4. Liu P, De Vis JB, Lu H. Cerebrovascular reactivity (CVR) MRI with CO2 challenge: A technical review. Neuroimage. 2019;187:104–115. doi: 10.1016/j.neuroimage.2018.03.047. [doi]
5. Liu P, Xu C, Lin Z, et al. Cerebrovascular reactivity mapping using intermittent breath modulation. Neuroimage. 2020;215:116787. doi: 10.1016/j.neuroimage.2020.116787. [doi]
6. Liu P, Liu G, Pinho MC, et al. Cerebrovascular Reactivity Mapping Using Resting-State BOLD Functional MRI in Healthy Adults and Patients with Moyamoya Disease. Radiology. 2021;299(2):419–425. doi: 10.1148/radiol.2021203568. [doi]
7. Power JD, Plitt M, Gotts SJ, et al. Ridding fMRI data of motion-related influences: Removal of signals with distinct spatial and physical bases in multiecho data. Proc Natl Acad Sci U S A. 2018;115(9):E2105–E2114. doi: 10.1073/pnas.1720985115. [doi]

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http://echo.ismrm.org/p/ISMRM2026/551-03-004