Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
363-02-008 ISMRM Abstract

Characterization of Subendocardial Microstructural Changes in Hypertrophic Cardiomyopathy (HCM) Patient-A Pilot Study

Primary: Cardiovascular - Myocardium
Secondary: Diffusion - Diffusion Analysis & Visualization
363-02-008 · All About Diffusion · Monday, 11 May, 9:15 AM–10:10 AM · Digital Posters Row D
Keywords: Hypertrophic cardiomyopathy Microstructural parameters Cardiac diffusion MRI
Accepted
Jia Liu 1, Zhongxu Bi2, jianxiu lian3, Bo Pan4, Jiaqi Tang5, Jianxing Qiu2
1Peking University First Hospital — Radiology Department, China
2Radiology Department, Peking University First Hospital, Beijing, China
3Clinical and Technical Support, Philips Healthcare (Beijing), Beijing, China
4Philips Healthcare (Beijing), Beijing, China
5Washington University in St. Louis, St. Louis, United States of America
Presenting Author: Jia Liu

Synopsis

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References

1. Silajdzija E, Vissing CR, Christensen EB, et al. Family Screening in Hypertrophic Cardiomyopathy: Identification of Relatives With Low Yield From Systematic Follow-Up. J Am Coll Cardiol. 2024;84(19):1854-1865. doi:10.1016/j.jacc.2024.08.011 [doi]
2. Thavendiranathan P, Zhang L, Zafar A, et al. Myocardial T1 and T2 Mapping by Magnetic Resonance in Patients With Immune Checkpoint Inhibitor-Associated Myocarditis. J Am Coll Cardiol. 2021;77(12):1503-1516. doi:10.1016/j.jacc.2021.01.050 [doi]
3. Dall'Armellina E, Ennis DB, Axel L, et al. Cardiac diffusion-weighted and tensor imaging: A consensus statement from the special interest group of the Society for Cardiovascular Magnetic Resonance. J Cardiovasc Magn Reson. 2025;27(1):101109. doi:10.1016/j.jocmr.2024.101109 [doi]
4. Dong Z, Tang Y, Sun P, et al. Early Identification of Myocardial Microstructural Alterations in Hypertrophic Cardiomyopathy with in Vivo Cardiac Diffusion-Tensor Imaging. Radiol Cardiothorac Imaging. 2025;7(1):e240009. doi:10.1148/ryct.240009 [doi]
5. Moulin K, Verzhbinsky IA, Maforo NG, Perotti LE, Ennis DB. Probing cardiomyocyte mobility with multi-phase cardiac diffusion tensor MRI. PLoS One. 2020;15(11):e0241996. Published 2020 Nov 12. doi:10.1371/journal.pone.0241996 [doi]
6. Das A, Kelly C, Teh I, et al. Phenotyping hypertrophic cardiomyopathy using cardiac diffusion magnetic resonance imaging: the relationship between microvascular dysfunction and microstructural changes. Eur Heart J Cardiovasc Imaging. 2022;23(3):352-362. doi:10.1093/ehjci/jeab210 [doi]
7. Wilson AJ, Sands GB, LeGrice IJ, Young AA, Ennis DB. Myocardial mesostructure and mesofunction. Am J Physiol Heart Circ Physiol. 2022;323(2):H257-H275. doi:10.1152/ajpheart.00059.2022 [doi]
8. Pope AJ, Sands GB, Smaill BH, LeGrice IJ. Three-dimensional transmural organization of perimysial collagen in the heart. Am J Physiol Heart Circ Physiol. 2008;295(3):H1243-H1252. doi:10.1152/ajpheart.00484.2008 [doi]

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http://echo.ismrm.org/p/ISMRM2026/363-02-008