Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
669-04-014 ISMRM Abstract

Interrogating preventative treatment efficacy in premalignant pancreatic cysts by hyperpolarized magnetic resonance

Primary: Body - Pancreas
Secondary: Interventional - Other Interventional
669-04-014 · Twists and Turns: Pancreas, Cholangio, and Bowel MRI · Thursday, 14 May, 2:35 PM–3:30 PM · Digital Posters Row J
Keywords: Hyperpolarized MR (Non-Gas) Pancreatic cancer Metabolic imaging KRAS Treatment Response Assessment
Accepted
José S Enriquez1, Julia R Zickus 1, Rian M Howell2, Olivereen Le Roux2, Shivanand Pudakalakatti1, Prasanta Dutta1, Florencia McAllister2,3, Pratip K Bhattacharya1
1Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, Houston, United States of America
2Genetics, The University of Texas MD Anderson Cancer Center, Houston, United States of America
3Ganstrointestinal (GI) Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, United States of America
Presenting Author: Julia R Zickus

Synopsis

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References

1. 1. Kiemen AL, Dequiedt L, Shen Y, Zhu Y, Matos-Romero V, Forjaz A, Campbell K, Dhana W, Cornish T, Braxton AM, Wu PH, Fishman EK, Wood LD, Wirtz D, Hruban RH. PanIN or IPMN? Redefining Lesion Size in 3 Dimensions. Am J Surg Pathol. 2024 Jul 1;48(7):839-845. doi: 10.1097/PAS.0000000000002245. Epub 2024 May 20. PMID: 38764379; PMCID: PMC11189722. [doi] [pmid]
2. 2. Wei D, Wang L, Zuo X, Maitra A, Bresalier RS. A Small Molecule with Big Impact: MRTX1133 Targets the KRASG12D Mutation in Pancreatic Cancer. Clin Cancer Res. 2024 Feb 16;30(4):655-662. doi: 10.1158/1078-0432.CCR-23-2098. PMID: 37831007; PMCID: PMC10922474. [doi] [pmid]
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4. 4. Makino Y, Rajapakshe KI, Chellakkan Selvanesan B, Okumura T, Date K, Dutta P, Abou-Elkacem L, Sagara A, Min J, Sans M, Yee N, Siemann MJ, Enriquez J, Smith P, Bhattacharya P, Kim M, Dede M, Hart T, Maitra A, Thege FI. Metabolic reprogramming by mutant GNAS creates an actionable dependency in intraductal papillary mucinous neoplasms of the pancreas. Gut. 2024 Dec 10;74(1):75-88. doi: 10.1136/gutjnl-2024-332412. PMID: 39277181; PMCID: PMC12014225. [doi] [pmid]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/669-04-014