562-05-015 ISMRM Abstract

Multi-echo spiral acquisition for rapid, sub-millimetre neonatal R2* whole brain mapping at 7T

Primary: Acquisition & Reconstruction - Pulse Sequence Design: Neuro

Secondary: Pediatrics - Neonatal

562-05-015 · Fetal and Neonatal Imaging · Wednesday, 13 May, 4:00 PM–4:55 PM · Digital Posters Row C

Keywords: Spiral acquisition R2star mapping Neonatal brain imaging

Accepted

David Leitão ^1,2,3, Chiara Casella^2,3,4, Antonia Massmann^2,3,5, Jucha Willers Moore^2,3, Alena Uus^1,2, Inka Granlund^3,6, Lucy Billimoria^3,6, Ines Tomazinho², Pierluigi Di Cio^3,6, Philippa Bridgen^3,6, Alexandra Bonthrone^2,3, Jonathon O'Muircheartaigh^2,4,5, Jo V Hajnal^1,2,3, Tomoki Arichi^1,2,3,7, Shaihan Malik^1,2,3

¹Research Dept of Imaging Physics & Engineering, School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom

²Research Dept of Early Life Imaging, School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom

³London Collaborative Ultra-High field System (LoCUS), King's College London, London, United Kingdom

⁴Department of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom

⁵MRC Centre for Neurodevelopmental Disorders, King's College London, London, United Kingdom

⁶Department of Radiology, Guy's and St. Thomas' NHS Foundation Trust, London, United Kingdom

⁷Guy's and St. Thomas' NHS Foundation Trust, London, United Kingdom

Presenting Author: David Leitão

Synopsis

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References

1. Mahmoud A, Tomi-Tricot R, Leitão D, Bridgen P et al. T1 and T2 measurements of the neonatal brain at 7 T. Magn Reson Med. 2024;93(5):2153-2162

2. Pickles ES, Willers Moore J, Bridgen P, Uus A et al. Characterisation of brain T2* Values across the neonatal period at 7 Telsa. Proceedings of the International Society for Magnetic Resonance in Medicine. Vol. 0884. 2024.

3. Malik SJ, Hand JW, Satnarine R, Price AN, Hajnal J V. Specific absorption rate and temperature in neonate models resulting from exposure to a 7T head coil. Magn Reson Med. 2021;86(3):1299-1313.

4. Leitão D, McElroy S, West DJ, Hajnal JV, Wood T, Arichi T, Malik S. Fast design of safe spirals on the scanner. Submitted to ISMRM 2026

5. Wood et al., (2021). Radial Interstices Enable Speedy Low-volume Imaging. Journal of Open Source Software, 6(66), 3500, https://doi.org/10.21105/joss.03500 [doi]

6. Bridgen P, Tomi-Tricot R, Uus A, et al. High resolution and contrast 7 tesla MR brain imaging of the neonate. Frontiers in Radiology. 2024;3. doi:10.3389/fradi.2023.1327075 [doi]

7. Uus AU, Kyriakopoulou V, Makropoulos A, et al. BOUNTI: Brain vOlumetry and aUtomated parcellatioN for 3D feTal MRI. bioRxiv. Published online January 1, 2023:2023.04.18.537347.

8. Raab P, Ropele S, Bültmann E, Salcher R, Lanfermann H, Wattjes MP. Analysis of deep grey nuclei susceptibility in early childhood: a quantitative susceptibility mapping and R2* study at 3 Tesla. Neuroradiology. 2022 May;64(5):1021-1031. doi: 10.1007/s00234-021-02846-0. [doi]

9. Yablonskiy DA, Haacke EM. Theory of NMR signal behavior in magnetically inhomogeneous tissues: the static dephasing regime. Magn Reson Med. 1994 Dec;32(6):749-63. doi: 10.1002/mrm.1910320610. PMID: 7869897. [doi] [pmid]

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http://echo.ismrm.org/p/ISMRM2026/562-05-015