Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026
· Cape Town, South Africa
552-01-013 / 552-01-013
ISMRM Abstract
First demonstration of Human brain diffusion-weighted MRS at 11.7T
Primary:
Contrast Mechanisms - Spectroscopy
Secondary:
Physics & Engineering - High-Field MRI
552-01-013 · Novel Approaches to Spectroscopy
· Wednesday, 13 May, 8:20 AM–9:56 AM · Power Pitch Theatre 2
552-01-013 · Novel Approaches to Spectroscopy
· Wednesday, 13 May, 8:20 AM–9:56 AM · Power Pitch Theatre 2
Keywords:SpectroscopyUltra-High Field (UHF)DW-MRSTime-dependent diffusion MRS
Accepted
Eloise Mougel 1, Franck Mauconduit2, Caroline LeSter2, Son Chu3, Shajan Gunamony3, Alfredo L Lopez Kolkovsky2, Nicolas Boulant2, Julien Valette1
1Université Paris-Saclay, Commissariat à l’Energie Atomique et aux Energies Alternatives (CEA), Centre National de la Recherche Scientifique (CNRS), Molecular Imaging Research Center (MIRCen), Fontenay aux Roses, France
2CEA NeuroSpin, Paris-Saclay University, CNRS, Gif-Sur-Yvette, France
3Imaging Center of Excellence, Glasgow, United Kingdom
Presenting Author: Eloise Mougel
Synopsis
Motivation:
Goals:
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2. Palombo M, Shemesh N, Ronen I, Valette J. Insights into brain microstructure from in vivo DW-MRS. NeuroImage. 2018;182:97-116. doi:10.1016/j.neuroimage.2017.11.028 [doi]
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9. Chu SC, Baskaran D, Mauconduit F, Gras V, Boulant N, Gunamony S. An 8-Channel Transmit Array in Combination with a 31-Channel Receive Array for Human Brain Imaging at 11.7T. In: Proc. Intl. Soc. Mag. Reson. Med. 2024:1415.
10. Amadon A, Cloos MA, Boulant N, Hang MF, Wiggins CJ, Fautz HP. Validation of a very fast B1-mapping sequence for parallel transmission on a human brain at 7T. In: Proc. Intl. Soc. Mag. Reson. Med. 20. Vol 3358. 2012. Accessed November 6, 2024. https://archive.ismrm.org/2012/3358.html
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13. Lundell H, Ingo C, Dyrby TB, Ronen I. Cytosolic diffusivity and microscopic anisotropy of N-acetyl aspartate in human white matter with diffusion-weighted MRS at 7 T. NMR in Biomedicine. 2021;34(5):e4304. doi:10.1002/nbm.4304 [doi]
14. Najac C, Branzoli F, Ronen I, Valette J. Brain intracellular metabolites are freely diffusing along cell fibers in grey and white matter, as measured by diffusion-weighted MR spectroscopy in the human brain at 7 T. Brain Structure and Function. 2016;221(3):1245-1254. doi:10.1007/s00429-014-0968-5 [doi]