470-03-095 ISMRM Abstract

Improving tractography reconstructions with asymmetric FOD tractography: preliminary evidence on the cortico-spinal tract

Primary: Diffusion - Tractography

Secondary: Diffusion - Diffusion Modeling

470-03-095 · Diffusion: Tractography Methods · Tuesday, 12 May, 9:15 AM–10:10 AM · Traditional Posters | Exhibition Hall

Accepted

Richard Stones¹, Flavio Dell'Acqua ¹

¹Neuroimaging & Biophysics Lab, Centre for Neuroimaging Sciences, King's College London, London, United Kingdom

Presenting Author: Flavio Dell'Acqua

Synopsis

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References

1. Tournier et al. Robust determination of the fibre orientation distribution in diffusion MRI: Non-negativity constrained super-resolved spherical deconvolution, NeuroImage, 35(4), 2007, 1459-1472, https://doi.org/10.1016/j.neuroimage.2007.02.016. [doi]

2. Dell'acqua et al. A modified damped Richardson-Lucy algorithm to reduce isotropic background effects in spherical deconvolution. NeuroImage. 49(2), 2010 :1446-58. https://doi.org/10.1016/j.neuroimage.2009.09.033. PMID: 19781650. [doi] [pmid]

3. Bastiani et al. Improved tractography using asymmetric fibre orientation distributions. NeuroImage, 158, 2017: 205-218, https://doi.org/10.1016/j.neuroimage.2017.06.050. [doi]

4. Poirier & Descoteaux M. A unified filtering method for estimating asymmetric orientation distribution functions. Neuroimage. 2024 287(5):120516. doi: 10.1016/j.neuroimage.2024.120516. PMID: 38244878. [doi] [pmid]

5. Stones & Dell’Acqua. Graph-based spatial regularization of Richardson-Lucy spherical deconvolution can improve fiber orientation estimates and generate asymmetric ODFs. ISMRM 2025 Diffusion Study Group Workshop, Kyoto.

6. Van Essen et al. The WU-Minn Human Connectome Project: an overview. Neuroimage. 2013 Oct 15;80:62-79. doi: 10.1016/j.neuroimage.2013.05.041. PMID: 23684880 [doi] [pmid]

7. Dell'Acqua et al. MegaTrack: a framework for the anatomically accurate and time-efficient virtual dissection and analysis of large-scale tractography datasets. bioRxiv 2025.05.27.656234; doi: https://doi.org/10.1101/2025.05.27.656234 [doi]

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http://echo.ismrm.org/p/ISMRM2026/470-03-095