Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
665-03-011 ISMRM Abstract

White Matter and Glymphatic Alterations in DoC: Links to Consciousness and Prognosis

Primary: Brain Function and fMRI - fMRI & Neuromodulation
Secondary: Brain Function and fMRI - fMRI Analysis
665-03-011 · fMRI: Applications in Neurology and Psychiatry III · Thursday, 14 May, 1:40 PM–2:35 PM · Digital Posters Row F
Keywords: Traumatic brain injury Glymphatic system DTI-ALPS Disorders of Consciousness
Accepted
Xiaoyang Ma 1, Yuhui Xiong2, Jing Zhang3,4
1Department of Magnetic Resonance, Lanzhou University Second Hospital, Lanzhou, China
2GE HealthCare MR Research, Beijing, China
3The Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou, China
4Department of Magnetic Resonance, Lanzhou, China
Presenting Author: Xiaoyang Ma

Synopsis

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References

1. Bagnato S. Progress and Challenges in Understanding Disorders of Consciousness following Acute Brain Injury. J Integr Neurosci 2023; 22 (4):84.
2. Botta D, Hutuca I, Ghoul EE, Sveikata L, Assal F, Lövblad KO, et al. Emerging non-invasive MRI techniques for glymphatic system assessment in neurodegenerative disease. J Neuroradiol 2025; 52 (3):101322.
3. Wang L, Yang Y, Chen S, Ge M, He J, Yang Z, et al. White matter integrity correlates with residual consciousness in patients with severe brain injury. Brain Imaging Behav 2018; 12 (6):1669-1677.
4. Guo Y, Wu L, Liu J, Liu J, Sun Z. Correlation between glymphatic dysfunction and cranial defect in severe traumatic brain injury: a retrospective case-control study based on a diffusion tensor image analysis along the perivascular space (DTI-ALPS) investigation. Quant Imaging Med Surg 2024; 14 (9):6756-6766.
5. Wu J, Ren R, Chen T, Su LD, Tang T. Neuroimmune and neuroinflammation response for traumatic brain injury. Brain Res Bull 2024; 217:111066.

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/665-03-011