Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
663-01-004 ISMRM Abstract

Evaluating 2D Flip Angle Modulated (FAM) MRI for Liver Proton Density Fat Fraction (PDFF) in Children and Young Adults

Primary: Pediatrics - Body
Secondary: Acquisition & Reconstruction - Motion Correction: Non-Neuro
663-01-004 · Diffusion MRI, Iron Quantification, and Steatosis in Human and Preclinical Studies · Thursday, 14 May, 8:30 AM–9:25 AM · Digital Posters Row D
Keywords: Pediatric Liver Quantitative Imaging MRI Fat Quantification
Accepted
Mishka G Hoo Kim 1, Tina Black2, Jonathan Dillman1, Diego Hernando3,4,5, Justine Kemp1, Mary Kate Manhard6, Yavuz Muslu2, Amol Pednekar1, Nathan T Roberts7, Jean A Tkach1, Cara Morin1
1Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, United States of America
2GE HealthCare, Cincinnati, Ohio, United States of America
3Department of Radiology, University of Wisconsin - Madison, Madison, United States of America
4Department of Medical Physics, University of Wisconsin - Madison, Madison, United States of America
5Calimetrix, Madison, United States of America
6Department of Radiology - Imaging Research Center, Cincinnati Children's Hospital Medical Center, Cincinnati, United States of America
7GE HealthCare, Waukesha, United States of America
Presenting Author: Mishka G Hoo Kim

Synopsis

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References

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2. Kiess, Wieland, Penke, Melanie, Sergeyev, Elena, Neef, Madlen, Adler, Melanie, Gausche, Ruth and Körner, Antje. "Childhood obesity at the crossroads" Journal of Pediatric Endocrinology and Metabolism, vol. 28, no. 5-6, 2015, pp. 481-484. https://doi.org/10.1515/jpem-2015-0168 [doi]
3. Sarin SK, Kumar M, Eslam M, George J, Al Mahtab M, Akbar SMF, Jia J, Tian Q, Aggarwal R, Muljono DH, Omata M, Ooka Y, Han KH, Lee HW, Jafri W, Butt AS, Chong CH, Lim SG, Pwu RF, Chen DS. Liver diseases in the Asia-Pacific region: a Lancet Gastroenterology & Hepatology Commission. Lancet Gastroenterol Hepatol. 2020 Feb;5(2):167-228. doi: 10.1016/S2468-1253(19)30342-5. Epub 2019 Dec 15. Erratum in: Lancet Gastroenterol Hepatol. 2020 Mar;5(3):e2. doi: 10.1016/S2468-1253(20)30021-2. PMID: 31852635; PMCID: PMC7164809. [doi] [pmid]
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5. Heidenreich JF, Tang J, Tamada D, Müller L, Grunz JP, do Vale Souza R, Anagnostopoulos A, Pirasteh A, Reeder SB, Hernando D. Motion-Insensitive Flip Angle Modulated Liver Proton Density Fat-Fraction and R2* Mapping During Free-Breathing MRI in a Clinical Setting. J Magn Reson Imaging. 2025 Nov;62(5):1452-1463. doi: 10.1002/jmri.70033. Epub 2025 Jul 12. PMID: 40650546; PMCID: PMC12456944. [doi] [pmid]
6. Shih SF, Wu HH. Free-breathing MRI techniques for fat and R2* quantification in the liver. MAGMA. 2024 Aug;37(4):583-602. doi: 10.1007/s10334-024-01187-2. Epub 2024 Jul 23. PMID: 39039272; PMCID: PMC11878285. [doi] [pmid]
7. Kilpattu Ramaniharan, A., Kemp, J., Kocaoglu, M. et al. Comparison of hepatic PDFF, T2*, and T2 estimates from breath-hold and free-breathing respiratory-gated MRI acquisitions in children and young adults. Abdom Radiol (2025). https://doi.org/10.1007/s00261-025-05232-z [doi]
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Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/663-01-004