Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
470-09-139 ISMRM Abstract

Effect of Cannabis Use on Brain Metabolites in People with HIV Using Whole-Brain Magnetic Resonance Spectroscopic Imaging

Primary: Neuro - Neuroinflammation
Secondary: Neuro - Infectious Disease
470-09-139 · MRI in Infectious Diseases · Tuesday, 12 May, 4:00 PM–4:55 PM · Traditional Posters | Exhibition Hall
Keywords: Neuroinflammation MRSI Neurometabolites HIV Cannabis
Accepted
Teddy Salan 1, Fernando M Moradel Cano2, Denise C Vidot3, Bria-Necole Diggs3, Dario N Ayala2, Sulaiman A Sheriff4, Hanzhi Gao5, Lisa J Reidy6, Eva Widerstrom-Noga7, Suresh Pallikkuth8, Allan E Rodriguez2, Robert L Cook9, Varan Govind1
1Department of Radiology, University of Miami, Miami, United States of America
2Division of Infectious Diseases, Department of Medicine, University of Miami, Miami, United States of America
3School of Nursing and Health Studies, University of Miami, Miami, United States of America
4Department of Radiation Oncology, Henry Ford Health, Detroit, United States of America
5Health Informatics Institute, University of South Florida, Tampa, United States of America
6Department of Pathology and Laboratory Medicine, University of Miami, Miami, United States of America
7The Miami Project to Cure Paralysis, Department of Neurological Surgery, University of Miami, Miami, United States of America
8Department of Microbiology and Immunology, University of Miami, Miami, United States of America
9Department of Epidemiology, College of Public Health and Health Professions & College of Medicine, University of Florida, Gainesville, United States of America
Presenting Author: Teddy Salan

Synopsis

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References

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2. Nath A. Eradication of human immunodeficiency virus from brain reservoirs. J Neurovirol. 2015 Jun;21(3):227-34. doi: 10.1007/s13365-014-0291-1. Epub 2014 Nov 4. PMID: 25366659; PMCID: PMC4418952. [doi] [pmid]
3. Chelala L, O'Connor EE, Barker PB, Zeffiro TA. Meta-analysis of brain metabolite differences in HIV infection. Neuroimage Clin. 2020;28:102436. doi: 10.1016/j.nicl.2020.102436. Epub 2020 Sep 15. PMID: 33383609; PMCID: PMC7596344. [doi] [pmid]
4. Kirkland AE, Browning BD, Green R, Agbeh SO, Squeglia LM. Neurometabolite Alterations Associated With Cannabis Use: A Proton Magnetic Resonance Spectroscopy Meta-Analysis. Hum Brain Mapp. 2025 Jun 1;46(8):e70236. doi: 10.1002/hbm.70236. PMID: 40421881; PMCID: PMC12107604. [doi] [pmid]
5. Colizzi M, Weltens N, McGuire P, Lythgoe D, Williams S, Van Oudenhove L, Bhattacharyya S. Delta-9-tetrahydrocannabinol increases striatal glutamate levels in healthy individuals: implications for psychosis. Mol Psychiatry. 2020 Dec;25(12):3231-3240. doi: 10.1038/s41380-019-0374-8. Epub 2019 Feb 15. PMID: 30770892; PMCID: PMC7714685. [doi] [pmid]
6. Maudsley AA, et al. Mapping of brain metabolite distributions by volumetric proton MR spectroscopic imaging (MRSI). Magnetic resonance in medicine: official journal of the Society of Magnetic Resonance in Medicine/Society of Magnetic Resonance in Medicine. 2009;61(3):548-559.
7. Maudsley AA, et al. Comprehensive processing, display and analysis for in vivo MR spectroscopic imaging. NMR in biomedicine. 2006;19(4):492-503.
8. Tzourio-Mazoyer N, Landeau B, Papathanassiou D, Crivello F, Etard O, Delcroix N, Mazoyer B, Joliot M. Automated anatomical labeling of activations in SPM using a macroscopic anatomical parcellation of the MNI MRI single-subject brain. Neuroimage. 2002 Jan;15(1):273-89.
9. Andrenyak DM, Moody DE, Slawson MH, O'Leary DS, Haney M. Determination of ∆-9-Tetrahydrocannabinol (THC), 11-hydroxy-THC, 11-nor-9-carboxy-THC and Cannabidiol in Human Plasma using Gas Chromatography-Tandem Mass Spectrometry. J Anal Toxicol. 2017 May 1;41(4):277-288.

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/470-09-139