Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
651-01-009 / 651-01-009 ISMRM Abstract

Comparative Analysis of APT and DWI for Assessing Ki-67, p53, and PD-L1 Expression in Bladder Cancer

Primary: Body - Urogenital
Secondary: Contrast Mechanisms - CEST / APT / NOE
651-01-009 · Pelvic MRI: Bladder, Endometrium, and Rectum · Thursday, 14 May, 8:30 AM–10:06 AM · Power Pitch Theatre 1
651-01-009 · Pelvic MRI: Bladder, Endometrium, and Rectum · Thursday, 14 May, 8:30 AM–10:06 AM · Power Pitch Theatre 1
Keywords: Bladder cancer Ki-67 expression Amide proton transfer-weighted imaging Diffusion-weighted imaging (DWI) PD-L1
Accepted
Jing-Lu Li 1,2, Yun Xu1,2, Yong-Sheng Xiang1,2, Peng Wu3, Ai-Jun Shen1,2, Pei-Jun Wang1,2, Fang Wang1,2
1Tongji University School of Medicine, Shanghai, China
2Department of Medical Imaging, Tongji Hospital, School of Medicine, Tongji University, Shanghai, China
3Clinical & Technical Support, Philips Healthcare, Guangzhou, China
Presenting Author: Jing-Lu Li

Synopsis

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References

1. Zhou J, Heo HY, Knutsson L, Van Zijl PCM, Jiang S. APT-weighted MRI: Techniques, current neuro applications, and challenging issues: APTw MRI for Neuro Applications. J Magn Reson Imaging. 2019;50(2):347-364. doi:10.1002 /jmri.26645
2. Togao O, Yoshiura T, Keupp J, et al. Amide proton transfer imaging of adult diffuse gliomas: correlation with histopathological grades. Neuro-Oncol. 2014;16 (3):441-448. doi:10.1093/neuonc/not158 [doi]
3. Li L, Chen W, Yan Z, et al. Comparative Analysis of Amide Proton Transfer MRI and Diffusion‐Weighted Imaging in Assessing p53 and Ki‐67 Expression of Rectal Adenocarcinoma. J Magn Reson Imaging. 2020;52(5):1487-1496. doi:10. 1002/jmri.27212
4. Apolo AB, Infante JR, Balmanoukian A, et al. Avelumab, an Anti–Programmed Death-Ligand 1 Antibody, In Patients With Refractory Metastatic Urothelial Carcinoma: Results From a Multicenter, Phase Ib Study. J Clin Oncol. 2017;35(19):2117-2124. doi:10.1200/JCO.2016.71.6795 [doi]
5. Yoshida S, Takahara T, Kwee TC, Waseda Y, Kobayashi S, Fujii Y. DWI as an Imaging Biomarker for Bladder Cancer. Am J Roentgenol. 2017;208(6):1218- 1228. doi:10.2214/AJR.17.17798 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/651-01-009