Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
669-04-001 ISMRM Abstract

Intravenous glucose stimulated pancreas BOLD MRI: preliminary findings in normoglycemic individuals with cystic fibrosis

Primary: Body - Pancreas
Secondary: Body - Endocrine
669-04-001 · Twists and Turns: Pancreas, Cholangio, and Bowel MRI · Thursday, 14 May, 2:35 PM–3:30 PM · Digital Posters Row J
Keywords: Diabetes Oxygenation Pancreas Perfusion Cystic Fibrosis
Accepted
David A Reiter 1,2, Anna M Horner3, Priyathama Vellanki3,4, Lisa R Staimez2,5
1Radiology & Imaging Sciences, Emory University, Atlanta, United States of America
2Emory Global Diabetes Research Center, Emory University, Atlanta, United States of America
3Emory University School of Medicine, Atlanta, United States of America
4Grady Memorial Hospital, Atlanta, United States of America
5Hubert Department of Global Health, Emory University, Rollins School of Public Health, United States of America
Presenting Author: David A Reiter

Synopsis

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References

1. Merjaneh, L., Q. He, Q. Long, L.S. Phillips, and A.A. Stecenko, Disposition index identifies defective beta-cell function in cystic fibrosis subjects with normal glucose tolerance. J Cyst Fibros, 2015. 14(1): p. 135–41.
2. Chen, B., W. Chen, Q. Chan, N. Zhou, J. He, and Z. Zhou, Functional MRI of human pancreas using BOLD contrast: Responses following glucose ingestion. J Magn Reson Imaging, 2017. 46(3): p. 831–836.
3. Horner, A.M., M.D. Nickel, V.K. Sharghi, L.R. Staimez, P. Vellanki, and D.A. Reiter. Free-Breathing Quantitative Blood Oxygen Level-Dependent (qBOLD) MRI of Healthy Adult Pancreas During Oral Glucose Stimulation. in International Society of Magnetic Resonance in Medicine. 2025.
4. Reiter, D.A., A.M. Horner, S.E. Edwards, O. Oladejo, L.R. Staimez, and P. Vellanki, Imaging β-Cell Response to Oral Glucose Stimulation with Quantitative Blood Oxygenation Dependent (qBOLD) MRI, in Ameican Diabetes Association. 2025.
5. American Diabetes Association Professional Practice, C., 2. Diagnosis and Classification of Diabetes: Standards of Care in Diabetes-2024. Diabetes Care, 2024. 47(Suppl 1): p. S20–S42.
6. Moran, A., D. Becker, S.J. Casella, P.A. Gottlieb, M.S. Kirkman, B.C. Marshall, B. Slovis, and C.C.C. Committee, Epidemiology, pathophysiology, and prognostic implications of cystic fibrosis-related diabetes: a technical review. Diabetes Care, 2010. 33(12): p. 2677–83.
7. Espes, D., E. Manell, A. Ryden, L. Carlbom, J. Weis, M. Jensen-Waern, L. Jansson, and O. Eriksson, Pancreatic perfusion and its response to glucose as measured by simultaneous PET/MRI. Acta Diabetol, 2019. 56(10): p. 1113–1120.
8. Jansson, L. and C. Hellerstrom, Stimulation by glucose of the blood flow to the pancreatic islets of the rat. Diabetologia, 1983. 25(1): p. 45–50.
9. Staimez, L.R., C. Huang, M.K. Bhasin, K.M. Narayan, P. Vellanki, and D.A. Reiter, Oxygen Consumption in Human Islets Is Increased in Type 2 Diabetes, in American Diabetes Association. 2025.

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/669-04-001