Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
367-05-013 ISMRM Abstract

Distinct Patterns of White Matter Microstructural Damage in MOGAD and MS Revealed by Tract-Based Spatial Statistics

Primary: Neuro - Neuroinflammation
Secondary: Pediatrics - Neuro
367-05-013 · Neuroinflammation: Myelin and Iron · Monday, 11 May, 4:10 PM–5:05 PM · Digital Posters Row H
Keywords: Multiple Sclerosis Diffusion Tensor Imaging Pediatric brain MRI White matter microstructure MOGAD
Accepted
Leonardo Tang1, Adam Goldman-Yassen1,2, Grace Gombolay3,4, Austin Wheeler1,2, Yuri Shishido4,5, Eswar Damaraju 2, Susan Palasis1,2, Hui Mao1
1Department of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, United States of America
2Department of Radiology, Children's Healthcare of Atlanta, Atlanta, United States of America
3Department of Pediatrics, Emory University School of Medicine, Atlanta, United States of America
4Department of Pediatrics, Children's Healthcare of Atlanta, Atlanta, United States of America
5Department of Neuropsychology, Emory University School of Medicine, Atlanta, United States of America
Presenting Author: Rachel M Goldberg

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References

1. Zhuo, Z. et al. Brain structural and functional alterations in MOG antibody disease. Mult Scler 27, 1350–1363 (2021). https://doi.org/10.1177/1352458520964415 [doi]
2. Jurynczyk, M. et al. Distinct brain imaging characteristics of autoantibody-mediated CNS conditions and multiple sclerosis. Brain 140, 617-627 (2017). https://doi.org/10.1093/brain/aww350 [doi]
3. Genova, H. M., DeLuca, J., Chiaravalloti, N. & Wylie, G. The relationship between executive functioning, processing speed, and white matter integrity in multiple sclerosis. J Clin Exp Neuropsychol 35, 631–641 (2013). https://doi.org/10.1080/13803395.2013.806649 [doi]
4. Carnero Contentti, E. et al. MRI to differentiate multiple sclerosis, neuromyelitis optica, and myelin oligodendrocyte glycoprotein antibody disease. Journal of Neuroimaging 33, 688-702 (2023). https://doi.org/https://doi.org/10.1111/jon.13137 [doi]
5. Ding, S. et al. Aberrant white matter microstructure detected by automatic fiber quantification in pediatric myelin oligodendrocyte glycoprotein antibody-associated disease. Multiple Sclerosis and Related Disorders 84, 105483 (2024). https://doi.org/https://doi.org/10.1016/j.msard.2024.105483 [doi]
6. Banwell, B. et al. Diagnosis of myelin oligodendrocyte glycoprotein antibody-associated disease: International MOGAD Panel proposed criteria. Lancet Neurol 22, 268-282 (2023). https://doi.org/10.1016/s1474-4422(22)00431-8 [doi]
7. Thompson, A. J. et al. Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteria. Lancet Neurol 17, 162-173 (2018). https://doi.org/10.1016/s1474-4422(17)30470-2 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/367-05-013