Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
565-01-004 ISMRM Abstract

Association of MRI Indices of the Perivascular Space Network with disease pathology and disability in Multiple Sclerosis

Primary: Neuro - Multiple Sclerosis
Secondary: Diffusion - DWI/DTI/DKI
565-01-004 · Neuroinflammation: Fluids and Flow · Wednesday, 13 May, 8:20 AM–9:15 AM · Digital Posters Row F
Keywords: Multiple Sclerosis Biomarker Glymphatic system Multi-parametric MRI Diffusivity along the perivascular spaces
Accepted
ZHANG HAO1, Cui Lingling 1, Jibin Cao1, ruisi gong1, Jinlin Jiao1, Li Mengyao1, Yueluan Jiang2
1Radiology, The First Hospital of China Medical University, Shenyang, China
2MR Research Collaboration Team, Siemens Healthineers Ltd., Beijing, China
Presenting Author: Cui Lingling

Synopsis

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References

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2. [2] Attarian S, Gacias M, Casaccia P. Multiple sclerosis: Neuroimmune crosstalk and therapeutic targeting[J]. Cell, 2023, 186(7): 1309-1327.PMID: 37001498 [pmid]
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7. [7] Carotenuto A, Cacciaguerra L, Pagani E, et al. Glymphatic system impairment in multiple sclerosis: relation with brain damage and disability[J]. Brain, 2022, 145(8): 2785-2795.PMID: 34919648 [pmid]
8. [8]Caporale AS, Chiarelli AM, Biondetti E, et al. Changes of brain parenchyma free water fraction reflect tissue damage and impaired processing speed in multiple sclerosis. Hum Brain Mapp. 2024 Jun 15;45(9):e26761.PMID: 38895882 [pmid]
9. [9]Liu XY, Ma GY, et al. Perivascular space is associated with brain atrophy in patients with multiple sclerosis. Quant Imaging Med Surg. 2022 Feb;12(2):1004-1019.PMID: 35111601. [pmid]
10. [10]Borrelli S, Guisset F, Vanden Bulcke C, et al. Enlarged perivascular spaces are associated with brain microangiopathy and aging in multiple sclerosis. Mult Scler. 2024 Jul;30(8):983-993.PMID: 38850029. [pmid]
11. [11]Mahmoudi F, Mirmosayyeb O, et al. Glymphatic system dysfunction in multiple sclerosis: A systematic review and meta-analysis[J]. Magnetic Resonance Imaging, 2024, 112: 38-45.PMID: 40780322 [pmid]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/565-01-004