Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
468-01-001 ISMRM Abstract

Microstructure Matters: DRTT Tract Quality as a Biomarker of VIM-DBS Response in Essential Tremor

Primary: Neuro - Other Neurodegeneration
Secondary: Neuro - White Matter
468-01-001 · Quantitative Neuroimaging of Neurodegeneration, Metabolism, and Brain Microstructure · Tuesday, 12 May, 8:20 AM–9:15 AM · Digital Posters Row I
Keywords: White Matter Deep Brain Stimulation Myelin Diffusion MRI Essential tremor
Accepted
Sohae Chung1, Ha Neul Song2, Mert Sisman3,4, Brian H Kopell2,5, Alon Mogilner6, Yvonne W Lui1, Yi Wang 7, Ki Sueng Choi2,5,8
1The Bernard and Irene Schwartz Center for Biomedical Imaging & Center for Biomedical Imaging and Center for Advanced Imaging Innovation and Research (CAI2R),Department of Radiology, New York University Grossman School of Medicine, New York, United States of America
2Nash Family Center for Advanced Circuit Therapeutics, Icahn School of Medicine at Mount Sinai, New York, United States of America
3Electrical & Computer Engineering, Cornell University, Ithaca, United States of America
4Department of Radiology, Weill Cornell Medicine, New York, United States of America
5Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, United States of America
6Department of Neurosurgery, New York University Grossman School of Medicine, New York, United States of America
7Department Radiology & Biomedical Engineering, Weill Cornell Medicine, Cornell University, New York, United States of America
8Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, United States of America
Presenting Author: Yi Wang

Synopsis

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References

1. Papavassiliou E, et al. Thalamic deep brain stimulation for essential tremor: relation of lead location to outcome. Neurosurgery 2008;62 Suppl 2:884-894.
2. Klein JC, et al. Diffusion tensor imaging of white matter involvement in essential tremor. Hum Brain Mapp 2011;32:896-904.
3. Şişman M, et al. Microstructure-informed myelin mapping (MIMM) from routine multi-echo gradient echo data using multiscale physics modeling of iron and myelin effects and QSM. MRM 2025;93(4):1499-1515.
4. Chung S, et al. Direct localization of the VIM/DRTT using quantitative susceptibility mapping in essential tremor: A pilot MRI study. AJNR 2025; A8934.
5. Stacy MA et al. Assessment of interrater and interrater reliability of the Fahn-Tolosa-Marin Tremor Rating Scale in essential tremor. Mov Disord 2007;22:833-838.

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/468-01-001