Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
531-02-014 / 531-02-014 ISMRM Abstract

Investigating Cerebral Blood Flow Changes in Alzheimer's Patients Undergoing Anti-Amyloid Therapy

Primary: Neuro - Alzheimer's Disease
Secondary: Neuro - Neurotherapeutics
531-02-014 · Imaging Neurodegeneration in Motion: Multimodal Biomarkers for Alzheimer’s Disease and Parkinson’s Disease · Wednesday, 13 May, 1:40 PM–3:16 PM · Roof Terrace
531-02-014 · Imaging Neurodegeneration in Motion: Multimodal Biomarkers for Alzheimer’s Disease and Parkinson’s Disease · Wednesday, 13 May, 1:40 PM–3:16 PM · Roof Terrace
Keywords: Neurodegeneration Treatment Response Alzheimer's Disease Arterial Spin Labelling (ASL) Anti-amyloid treatment
Accepted
Elena R Andree 1,2,3, Conan Chen2,3, Katherine Bangen3,4, Ryan A Barnes2,3, Jason Handwerker3, Eric Wong2,3, Thomas Liu2,3, Divya Bolar2,3
1University of Oxford, Oxford, United Kingdom
2Center for Functional MRI, Department of Radiology, University of California San Diego, United States of America
3University of California, San Diego, United States of America
4VA San Diego Healthcare System, San Diego, California, United States of America
Presenting Author: Elena R Andree

Synopsis

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References

1. Alsop DC, Detre JA, Golay X, Günther M, Hendrikse J, Hernandez-Garcia L, Lu H, MacIntosh BJ, Parkes LM, Smits M, van Osch MJ, Wang DJ, Wong EC, Zaharchuk G. Recommended implementation of arterial spin-labeled perfusion MRI for clinical applications: A consensus of the ISMRM perfusion study group and the European consortium for ASL in dementia. Magn Reson Med. 2015 Jan;73(1):102-16. doi:10.1002/mrm.25197. [doi]
2. Van Dyck, C.H., et al., 2023. Lecanemab in early Alzheimer’s disease. New England Journal of Medicine. 388 (1), 9-21. DOI: 10.1056/NEJMoa2212948. [doi]
3. Noorbakhsh A, Farid N, Bolar DS. Apparent posterior cerebral artery territory perfusion asymmetry on arterial spin labeling MRI is a common non-pathologic finding in patients with a unilateral fetal posterior cerebral artery. Neuroradiology. 2022 Mar;64(3):513-520. doi: 10.1007/s00234-021-02794-9. [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/531-02-014