Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
652-02-017 / 652-02-017 ISMRM Abstract

Intravenous administration of 2H-glucose for human hepatic, cardiac and brain DMI at 3 T

Primary: Contrast Mechanisms
Secondary: Body
652-02-017 · Heart and Brain Interactions · Thursday, 14 May, 1:40 PM–3:16 PM · Power Pitch Theatre 2
652-02-017 · Heart and Brain Interactions · Thursday, 14 May, 1:40 PM–3:16 PM · Power Pitch Theatre 2
Keywords: Deuterium Metabolic Imaging Non-Proton MRI
Accepted
Pascal Wodtke1, Sebastian Bauer 1, Jonathan Birchall1, Maria J Zamora Morales1, Ashley Grimmer1, Elizabeth Latimer1, Marta Wylot1, Ioanna Demetriou2, Maria Chondronikola2, Mary A McLean1, Ferdia Gallagher1
1Department of Radiology, University of Cambridge, Cambridge, United Kingdom
2Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom
Presenting Author: Sebastian Bauer

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References

1. De Feyter, H. M. & De Graaf, R. A. Deuterium metabolic imaging – Back to the future. J. Magn. Reson. 326, 106932 (2021)
2. De Feyter H et al. Deuterium metabolic imaging (DMI) for MRI-based 3D mapping of metabolism in vivo. Sci. Adv. 4. Eaat7314 (2018)
3. Gursan, A. et al. Deuterium body array for the simultaneous measurement of hepatic and renal glucose metabolism and gastric emptying with dynamic 3D deuterium metabolic imaging at 7 T. NMR Biomed. 36, e4926 (2023)
4. Wodtke, P. et al. Deuterium Metabolic Imaging of the Human Abdomen at Clinical Field Strength. Investigative Radiology. (2025) Online before in print.
5. Purvis, L. A. B. et al. OXSA: An open-source magnetic resonance spectroscopy analysis toolbox in MATLAB. PLOS ONE 12, e0185356 (2017)
6. Vanhamme, L., van den Boogaart, A. & Van Huffel, S. Improved Method for Accurate and Efficient Quantification of MRS Data with Use of Prior Knowledge. J. Magn. Reson. 129, 35–43 (1997)
7. Martin, E. et al. Choosing an optimal input for an intravenous glucose tolerance test to aid parameter identification. J. Pharmacol. Pharm., 69, 1275–1283 (2017)

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/652-02-017