Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
564-05-013 ISMRM Abstract

Generation of Synthetic Brain Tumour MR Spectra using Convex NMF and Statistical Modelling

Primary: Acquisition & Reconstruction - Spectroscopy and spectroscopic imaging
Secondary: Neuro - Tumors
564-05-013 · The qMRI Variety Show: A Little Bit of Everything · Wednesday, 13 May, 4:00 PM–4:55 PM · Digital Posters Row E
Keywords: Diagnostic performance Brain Tumor classification Data Scarcity Diagnostic Accuracy Synthetic Spectra
Accepted
Matthew McCarthy 1, Lili F Tóth1,2,3, Alfredo Vellido3,4,5, Margarida Julià-Sapé1,2,3
1Institut de Biotecnologia i Biomedicina, Universitat Autònoma de Barcelona, Cerdanyola del Vallès, Spain
2Departament de Bioquímica i Biologia Molecular, Universitat Autònoma de Barcelona, Cerdanyola del Vallès, Spain
3CIBER de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Spain
4Department of Computer Science, Universitat Politècnica de Catalunya (UPC), Barcelona, Spain
5Intelligent Data Science and Artificial Intelligence Research Center (IDEAI-UPC), Barcelona, Spain
Presenting Author: Matthew McCarthy

Synopsis

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References

1. Julià-Sapé M and Griffiths JR. Classification of brain tumours from MR spectra: the INTERPRET collaboration and its outcomes. NMR in Biomedicine, 28(12):1772–1787, 2015. PMID: 26768492 DOI: 10.1002/nbm.3439 [doi] [pmid]
2. Shamaei A, Starcukova J, and Starcuk Z. Physics-informed deep learning approach to quantification of human brain metabolites from magnetic resonance spectroscopy data. Computers in Biology and Medicine, 158:106837, 2023. PMID: 37044049 DOI: 10.1016/j.compbiomed.2023.106837 [doi] [pmid]
3. Ortega-Martorell S, Lisboa PJ, Vellido A, Julià-Sapé M, and Arùs C. Non-negative matrix factorisation methods for the spectral decomposition of MRS data from human brain tumours. BMC Bioinformatics, 13(1), 2012. PMID: 22401579 PMCID: PMC3364901 DOI: 10.1186/1471-2105-13-38 [doi] [pmid]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/564-05-013