531-01-002 / 531-01-002 ISMRM Abstract

Open Source CEST-MRI using BART: Sequence Definition, Reconstruction and Quantification

Primary: Contrast Mechanisms - CEST / APT / NOE

Secondary: Acquisition & Reconstruction - Open source software, sequences, and reconstruction algorithms

531-01-002 · Quantitative Imaging: Applications · Wednesday, 13 May, 8:20 AM–9:56 AM · Roof Terrace

Keywords: CEST & MT CEST / APT / NOE Open-source software Reproducibility CEST MRI

Accepted

Markus Huemer ¹, Daniel Mackner¹, Moritz Blumenthal¹, Sarah Warger¹, Philip Schaten¹, Clemens Stilianu¹, Martin Uecker¹, Rudolf Stollberger¹

¹Institute of Biomedical Imaging, Graz University of Technology, Graz, Austria

Presenting Author: Markus Huemer

Synopsis

Motivation:

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References

1. Zaiss, M., Schmitt, B., & Bachert, P. (2011). Quantitative separation of CEST effect from magnetization transfer and spillover effects by Lorentzian-line-fit analysis of z-spectra. Journal of Magnetic Resonance, 211(2), 149–155. https://doi.org/10.1016/j.jmr.2011.05.001 [doi]

2. BART Toolbox for Computational Magnetic Resonance Imaging. https://doi.org/10.5281/zenodo.592960 [doi]

3. Uecker M, Mackner D, Telezki V. (2025). Open MR days: BART workshop. github.com/mrirecon/bart-workshop/tree/master/dach\_ismrm2025, 27th annual meeting of the German-Austrian-Swiss section (DACH-ISMRM), Kiel.

4. Stilianu, C., Huemer, M., Zaiss, M., & Stollberger, R. (2025). Generalization of Optimal Control Saturation Pulse Design for Robust and High CEST Contrast. Magnetic Resonance in Medicine, https://doi.org/10.1002/mrm.701505. [doi]

5. Layton, K. J., Kroboth, S., Jia, F., Littin, S., Yu, H., Leupold, J., Nielsen, J. F., Stöcker, T., & Zaitsev, 5. (2017). Pulseq: A rapid and hardware-independent pulse sequence prototyping framework. Magnetic Resonance in Medicine, 77(4), 1544–1552. https://doi.org/10.1002/MRM.26235 [doi]

6. Sun, P. Z. (2021). Quasi-steady state chemical exchange saturation transfer (QUASS CEST) analysis—correction of the finite relaxation delay and saturation time for robust CEST measurement. Magnetic Resonance in Medicine, 85(6), 3281–3289. https://doi.org/10.1002/MRM.28653 [doi]

7. Zaiss, M., Xu, J., Goerke, S., Khan, I. S., Singer, R. J., Gore, J. C., Gochberg, D. F.,& Bachert, P. (2014). Inverse Z-spectrum analysis for spillover-, MT-, and T1-corrected steady-state pulsed CEST-MRI – application to pH-weighted MRI of acute stroke. NMR in Biomedicine, 27(3), 240–252. https://doi.org/10.1002/NBM.3054 [doi]

8. Scholand, N., Schaten, P., Graf, C., Mackner, D., Holme, H. C. M., Blumenthal, M., Mao, A., Assländer, J., & Uecker, M. (2025). Rational approximation of golden angles: Accelerated reconstructions for radial MRI. Magnetic Resonance in Medicine, 93(1), 51–66. https://doi.org/10.1002/MRM.30247 [doi]

9. Uecker, M., Hohage, T., Block, K. T., & Frahm, J. (2008). Image reconstruction by regularized nonlinear inversion—Joint estimation of coil sensitivities and image content. Magnetic Resonance in Medicine, 60(3), 674–682. https://doi.org/10.1002/MRM.21691 [doi]

10. Schloegl, M., Holler, M., Schwarzl, A., Bredies, K., & Stollberger, R. (2017). Infimal convolution of total generalized variation functionals for dynamic MRI. Magnetic Resonance in Medicine, 78(1), 142–155. https://doi.org/10.1002/MRM.26352 [doi]

11. Wang, X., Roeloffs, V., Klosowski, J., Tan, Z., Voit, D., Uecker, M., \& Frahm, J. (2018). Model-based T1 mapping with sparsity constraints using single-shot inversion-recovery radial FLASH. Magnetic Resonance in Medicine, 79(2), 730–740. https://doi.org/10.1002/MRM.26726 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/531-01-002