Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
662-01-010 ISMRM Abstract

Quantitative analysis of neurochemical changes in epilepsy imaged by 7T MRSI

Primary: Contrast Mechanisms - Spectroscopy
Secondary: Neuro - Epilepsy
662-01-010 · Advanced Quantitative and Diffusion MRI for Epilepsy: From Lesion Detection to Clinical Translation · Thursday, 14 May, 8:30 AM–9:25 AM · Digital Posters Row C
Keywords: Epilepsy MRSI Whole-Brain Segmentation Quantitative Analysis
Accepted
Haniye Shayeste 1,2, Stefanie Chambers1,2, Philipp Lazen1,2, Matthias Tomschik1, Jonathan Wais1, Gregor Kasprian3, Lukas Haider3, Leo Hofer3, Pascal Baltzer2, Christoph Baumgartner4, Johannes Koren4, Vitalij Zeiser1, Florian Mayer1, Martha Feucht1, Christian Dorfer1, Ekaterina Pataraia1, Wolfgang Bogner2,5, Karl Rössler1,5, Gilbert Hangel1,2,5
1Medical University of Vienna, Vienna, Austria
2MRCE, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria
3Division of Neuroradiology and Musculoskeletal Radiology, Medical University of Vienna, Vienna, Austria
4Department of Neurology, Krankenhaus Hietzing, Vienna, Austria
5Christian Doppler Laboratory for MR Imaging Biomarkers, Vienna, Austria
Presenting Author: Haniye Shayeste

Synopsis

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References

1. Milligan, Tracey A. "Epilepsy: a clinical overview." The American Journal of Medicine 134.7 (2021): 840-847.
2. McGovern, Robert A., Garrett P. Banks, and Guy M. McKhann. "New techniques and progress in epilepsy surgery." Current neurology and neuroscience reports 16 (2016): 1-9.
3. Hangel, Gilbert, et al. "Implementation of a 7T Epilepsy Task Force consensus imaging protocol for routine presurgical epilepsy work-up: effect on diagnostic yield and lesion delineation." Journal of neurology (2023): 1-15.
4. Hainc, Nicolin, et al. "Imaging in medically refractory epilepsy at 3 Tesla: a 13-year tertiary adult epilepsy center experience." Insights into Imaging 13.1 (2022): 99.
5. Urbach, Horst, et al. "Diagnostic Accuracy of Epilepsy-dedicated MRI with Post-processing." Clinical Neuroradiology 33.3 (2023): 709-719.
6. Pan, Jullie W., et al. "7 T MR spectroscopic imaging in the localization of surgical epilepsy." Epilepsia 54.9 (2013): 1668-1678.
7. Jamalipour Soufi, Ghazaleh, et al. "Correlation of magnetic resonance spectroscopy and magnetic resonance imaging with findings of electroencephalography in patients with temporal lobe epilepsy." Journal of Medical Radiation Sciences 71.1 (2024): 51-56.
8. Colon, A. J., et al. "MRS-lateralisation index in patients with epilepsy and focal cortical dysplasia or a MEG-focus using bilateral single voxels." Epilepsy research 89.1 (2010): 148-153.
9. Hingerl, Lukas, et al. "Clinical high-resolution 3D-MR spectroscopic imaging of the human brain at 7 T." Investigative radiology 55.4 (2020): 239-248.
10. Hangel, Gilbert, et al. "CRT-FID-MRSI at 7T for the high-resolution metabolic imaging of epilepsy: Preliminary results." ISMRM, Virtual Meeting. Vol. 723. 2021.
11. MATLAB. The MathWorks Inc. (2017).
12. Provencher, S. W. Automatic quantitation of localized in vivo 1H spectra with LCModel. NMR Biomed. 14, 260–264 (2001).
13. Hangel, Gilbert, et al. "Inter‐subject stability and regional concentration estimates of 3D‐FID‐MRSI in the human brain at 7 T." NMR in Biomedicine 34.12 (2021): e4596.
14. Fischl, Bruce. "FreeSurfer." Neuroimage 62.2 (2012): 774-781.

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/662-01-010