Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
664-01-004 ISMRM Abstract

Cerebellar atrophy modulates freezing of gait in multiple system atrophy through cognitive dysfunction

Primary: Brain Function and fMRI - fMRI Analysis
Secondary: Neuro - Parkinson's Disease
664-01-004 · Cerebellar Function · Thursday, 14 May, 8:30 AM–9:25 AM · Digital Posters Row E
Keywords: Cognition Cerebellum Neuroimaging Multiple system atrophy Freezing of Gait
Accepted
huaguang yang 1, Weiyin Vivian Liu2, Liang Li1, Zhi Wen1, Lanhua Hu1, Yunfei Zha1
1Department of Radiology, Renmin Hospital of Wuhan University, Wuhan, China
2MR Research, GE HealthCare, Beijing, China
Presenting Author: huaguang yang

Synopsis

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References

1. Herman T, Barer Y, Bitan M, et al. A meta-analysis identifies factors predicting the future development of freezing of gait in Parkinson's disease [J]. NPJ Parkinsons Dis, 2023, 9(1): 158. DOI:10.1038/s41531-023-00600-2 [doi]
2. Yarnall A J, Morris R. A cholinergic contribution to postural control and freezing of gait in Parkinson's disease [J]. Brain, 2023, 146(8): 3110-1. DOI:10.1093/brain/awad223 [doi]
3. Moore O, Peretz C, Giladi N. Freezing of gait affects quality of life of peoples with Parkinson's disease beyond its relationships with mobility and gait [J]. Mov Disord, 2007, 22(15): 2192-5. DOI:10.1002/mds.21659 [doi]
4. Rahman S, Griffin H J, Quinn N P, et al. Quality of life in Parkinson's disease: the relative importance of the symptoms [J]. Mov Disord, 2008, 23(10): 1428-34. DOI:10.1002/mds.21667 [doi]
5. Naismith S L, Shine J M, Lewis S J. The specific contributions of set-shifting to freezing of gait in Parkinson's disease [J]. Mov Disord, 2010, 25(8): 1000-4. DOI:10.1002/mds.23005 [doi]
6. Giladi N, Huber-Mahlin V, Herman T, et al. Freezing of gait in older adults with high level gait disorders: association with impaired executive function [J]. J Neural Transm (Vienna), 2007, 114(10): 1349-53. DOI:10.1007/s00702-007-0772-y [doi]
7. Mancini M, Mckay J L, Cockx H, et al. Technology for measuring freezing of gait: Current state of the art and recommendations [J]. J Parkinsons Dis, 2025, 15(1): 19-40. DOI:10.1177/1877718X241301065 [doi]
8. Lewis S J, Barker R A. A pathophysiological model of freezing of gait in Parkinson's disease [J]. Parkinsonism Relat Disord, 2009, 15(5): 333-8. DOI:10.1016/j.parkreldis.2008.08.006 [doi]

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http://echo.ismrm.org/p/ISMRM2026/664-01-004