402-03-007 ISMRM Abstract

Macromolecules matter: impact of macromolecular background fitting on detecting metabolic age-related differences at 7 T

Primary: Contrast Mechanisms - Spectroscopy

Secondary: Acquisition & Reconstruction - Signal Modeling

402-03-007 · Metabolic Imaging and MR Spectroscopy: Methods and Application · Tuesday, 12 May, 1:40 PM–3:30 PM · Hall 1B

Keywords: Aging Ultra-high field MRS Spectral modeling Metabolic biomarker of healthy aging

Accepted

Guglielmo Genovese ^1,2, Melissa Terpstra², Pavel Filip^2,3, John R McCarten⁴, Laura S Hemmy⁴, Silvia Mangia², Malgorzata Marjanska²

¹Department of Neuromedicine and Movement Science, Norwegian University of Science and Technology NTNU, Norway

²Center for Magnetic Resonance Research, Dept. of Radiology, University of Minnesota, Minneapolis, United States of America

³Department of Neurology, Charles University, First Faculty of Medicine and General University Hospital, Prague, Czech Republic

⁴Geriatric Research, Education and Clinical Center, Veterans Affairs Health Care System, Minneapolis, United States of America

Presenting Author: Guglielmo Genovese

Synopsis

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References

1. [1] Marjańska and Terpstra, NMR Biomed. (2019), doi: 10.1002/nbm.4197 [2] Cudalbu et al., NMR Biomed. (2021), doi: 10.1002/nbm.4393 [3] Marjańska et al., NMR Biomed. (2017), doi: 10.1002/nbm.3865 [4] Genovese et al., Magn. Reson. Med. (2024), doi: 10.1002/mrm.30061 [5] Hui et al., Magn. Reson. Med. (2022), doi: 10.1002/mrm.29093 [6] Zöllner HJ et al., NMR Biomed. (2023), doi: 10.1002/nbm.4854 [7] Adriany G et al., Magn Reson Med. (2008), doi: 10.1002/mrm.21488 [8] Metzger GJ et al., Magn Reson Med. (2008), doi: 10.1002/mrm.21476 [9] Gruetter R et al., Magn Reson Med. (2000), doi: 10.1002/(SICI)1522-2594(200002)43:2<319::AID-MRM22>3.0.CO;2-1 [10] Tkáč I et al., Magn Reson Med. (2001), doi: 10.1002/mrm.1213 [11] Provencher SW et al., Magn Reson Med. (1993), doi: 10.1002/mrm.1910300604 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/402-03-007