Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
565-03-014 ISMRM Abstract

Quantitative T1 imaging of the human brain at 11.7 Tesla using a MP2RAGE sequence with dynamic pTx and FatNav

Primary: Physics & Engineering - High-Field MRI
Secondary: Contrast Mechanisms - Relaxometry
565-03-014 · Mesoscale Functional MRI and Acquisition Strategies · Wednesday, 13 May, 1:40 PM–2:35 PM · Digital Posters Row F
Keywords: High-Field MRI Motion Correction Parallel Transmit & Multiband RF Pulse Design & Fields Relaxation times
Accepted
Aurélien Massire1,2, Franck Mauconduit 1, Vincent Gras1, Natalia Dudysheva1, Joseph Brégeat1, Son Chu3, Shajan Gunamony3, Daniel Gallichan4, Alexandre Vignaud1, Nicolas Boulant1
1CEA NeuroSpin, Paris-Saclay University, CNRS BAOBAB, Gif-sur-Yvette, France
2Siemens Healthineers SAS, Courbevoie, France
3Imaging Centre of Excellence, University of Glasgow, Glasgow, United Kingdom
4CUBRIC, Cardiff, United Kingdom
Presenting Author: Franck Mauconduit

Synopsis

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References

1. Boulant, et al. In vivo imaging of the human brain with the Iseult 11.7-T MRI scanner. Nat Methods. 2024;21(11):2013–2016. 10.1038/s41592-024-02472-7 [doi]
2. Le Ster, et al. Magnetic field strength dependent SNR gain at the center of a spherical phantom and up to 11.7T. Magn Reson Med. 2022;88(5):2131–2138. 10.1002/mrm.29391 [doi]
3. Feinberg, et al. Next-generation MRI scanner designed for ultra-high-resolution human brain imaging at 7 Tesla. Nat Methods. 2023;20(12):2048–2057. 10.1038/s41592-023-02068-7 [doi]
4. Waks, et al. RF coil design strategies for improving SNR at the ultrahigh magnetic field of 10.5T. Magn Reson Med. 2025;93(2):873–888. 10.1002/mrm.30315 [doi]
5. Cosottini et al. MR imaging of the substantia nigra at 7 T enables diagnosis of Parkinson disease. Radiology. 2014;271(3):831–8. 10.1148/radiol.14131448 [doi]
6. Opheim, et al. 7T Epilepsy Task Force Consensus Recommendations on the Use of 7T MRI in Clinical Practice. Neurology. 2021;96(7):327–341. 10.1212/WNL.0000000000011413 [doi]
7. Sati, et al. The central vein sign and its clinical evaluation for the diagnosis of multiple sclerosis: a consensus statement from the North American Imaging in Multiple Sclerosis Cooperative. Nat Rev Neurol. 2016;12(12):714–722. 10.1038/nrneurol.2016.166 [doi]
8. The Iseult Consortium. The CEA-Siemens Healthineers MAGNETOM Iseult 11.7-Tesla MRI System: A 20-year Odyssey to Image the Human Brain. MAGNETOM Flash (91) 2/2025
9. Gras, et al. First experience of PTX RF pulse design at 11.T MRI for whole brain imaging in vivo. In Proceedings of ISMRM 2024, Singapore, p3926.
10. Mauconduit, et al. Pushing the image quality by integrating FatNav and PTx Universal Pulses in MPRAGE and MP2RAGE Sequences at 7T. In Proceedings of ISMRM 2024, Singapore, p4895.
11. Marques, et al. MP2RAGE, a self bias-field corrected sequence for improved segmentation and T1-mapping at high field. Neuroimage. 2010;49:1271-1281. 10.1016/j.neuroimage.2009.10.002 [doi]
12. Massire, et al. T1-based synthetic magnetic resonance contrasts improve multiple sclerosis and focal epilepsy imaging at 7 T. Investigative Radiology. 2021;56(2):127-133. 10.1097/RLI.0000000000000718 [doi]
13. Bapst, et al. Pushing MP2RAGE boundaries: Ultimate time-efficient parameterization combined with exhaustive T1 synthetic contrasts. Magn Reson Med. 2024;91(4):1608-1624. 10.1002/mrm.29948 [doi]
14. Chu, et al. An 8-Channel Transmit Array in Combination with a 31-Channel Receive Array for Human Brain Imaging at 11.7T. In Proceedings of ISMRM 2024, Singapore, p1415.
15. Gras, et al. A Mathematical Analysis of Clustering-Free Local SAR Compression Algorithms for MRI Safety in Parallel Transmission. IEEE Transactions on Medical Imaging. 2024;43(2):714-722. 10.1109/TMI.2023.3319017 [doi]
16. Brégeat, et al. Efficient simultaneous optimization of K-space trajectories and parallel transmission RF waveforms using the parametric 'fastGRAPE' approach. In Proceedings of ESMRMB 2024, Barcelona, Spain, p0420.
17. Dudysheva et al. Fast Gradient Ascent Pulse Engineering for parallel transmission pulse design in the small and large tip angle regimes. In Proceedings of ISMRM 2025, Honolulu, Hawaii, p3439.
18. The RetroMocoBox toolbox accessed at https://github.com/dgallichan/retroMoCoBox
19. Manjón and Coupe. volBrain: an online MRI brain volumetry system. Frontiers in Neuroinformatics, 10, 30, 2016. 10.3389/fninf.2016.00030 [doi]
20. Caan, et al. MP2RAGEME: T1 , T2* , and QSM mapping in one sequence at 7 tesla. Hum Brain Mapp 2019;40(6):1786-1798. 10.1002/hbm.24490 [doi]
21. Bottomley, et al. A review of normal tissue hydrogen NMR relaxation times and relaxation mechanisms from 1-100 MHz: dependence on tissue type, NMR frequency, temperature, species, excision, and age. Med Phys 1984;11(4):425-448. 10.1118/1.595535 [doi]

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http://echo.ismrm.org/p/ISMRM2026/565-03-014