Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026
· Cape Town, South Africa
401-04-008
ISMRM Abstract
Early sarcopenia risk identification in cirrhotic patients using 31P-MRS skeletal muscle metabolism on a clinical MRI system
Primary:
Musculoskeletal - Muscle
Secondary:
Acquisition & Reconstruction - Spectroscopy and spectroscopic imaging
401-04-008 · Metabolism
· Tuesday, 12 May, 4:00 PM–5:50 PM · Hall 1A
Keywords:LiverMuscleMRSExercisePhosphorous Magnetic Resonance Spectroscopy
Accepted
Jihun Kwon 1, Kumi Ozaki2, Yasutomo Katsumata3, Naoki Oishi2, Yukichi Tanahashi2, Marc Van Cauteren1, Satoshi Goshima2
1Philips Japan, Tokyo, Japan
2Department of Radiology, Hamamatsu University School of Medicine, Hamamatsu, Japan
3Philips Healthcare, Best, Netherlands
Presenting Author: Jihun Kwon
Synopsis
Motivation:
Goals:
Approach:
Results:
Full abstract & presentation
The full text, figures, and any recorded presentation for this abstract are not shown here. Log in if you are a member or registered attendee with access.
Full abstracts, figures, and presentations for Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition are available to registered attendees. This content becomes freely available to the public roughly two years after the meeting.
To request or purchase access, contact the ISMRM Central Office at info@ismrm.org.
1. Park JH, Brown RL, Park CR, et al. Functional pools of oxidative and glycolytic fibers in human muscle observed by 31P magnetic resonance spectroscopy during exercise. Proc Natl Acad Sci U S A. 1987;84(24):8976-8980. doi:10.1073/pnas.84.24.8976 [doi]
2. Achten E, Van Cauteren M, Willem R, et al. 31P-NMR Spectroscopy and the metabolic properties of different muscle fibers. J Appl Physiol. 1990;68(2):644-649. doi:10.1152/jappl.1990.68.2.644 [doi]
3. Habets LE, Bartels B, Asselman FL, et al. Magnetic resonance reveals mitochondrial dysfunction and muscle remodelling in spinal muscular atrophy. Brain. 2022;145(4):1422-1435. doi:10.1093/brain/awab411 [doi]
4. Cameron D, Welch AA, Adelnia F, et al. Age and Muscle Function Are More Closely Associated With Intracellular Magnesium, as Assessed by 31P Magnetic Resonance Spectroscopy, Than With Serum Magnesium. Front Physiol. 2019;10(November):1-13. doi:10.3389/fphys.2019.01454 [doi]
5. Stephenson MC, Ho JXM, Migliavacca E, et al. Evidence for inefficient contraction and abnormal mitochondrial activity in sarcopenia using magnetic resonance spectroscopy. J Cachexia Sarcopenia Muscle. 2023;14(3):1482-1494. doi:10.1002/jcsm.13220 [doi]
6. Malmstrom TK, Miller DK, Simonsick EM, Ferrucci L, Morley JE. SARC-F: A symptom score to predict persons with sarcopenia at risk for poor functional outcomes. J Cachexia Sarcopenia Muscle. 2016;7(1):28-36. doi:10.1002/jcsm.12048 [doi]
7. Cho MR, Lee S, Song SK. A Review of Sarcopenia Pathophysiology, Diagnosis, Treatment and Future Direction. J Korean Med Sci. 2022;37(18):1-10. doi:10.3346/jkms.2022.37.e146 [doi]
8. Dasarathy S. Consilience in sarcopenia of cirrhosis. J Cachexia Sarcopenia Muscle. 2012;3(4):225-237. doi:10.1007/s13539-012-0069-3 [doi]
9. Hanai T, Shiraki M, Ohnishi S, et al. Rapid skeletal muscle wasting predicts worse survival in patients with liver cirrhosis. Hepatol Res. 2016;46(8):743-751. doi:10.1111/hepr.12616 [doi]
10. Naressi A, Couturier C, Castang I, De Beer R, Graveron-Demilly D. Java-based graphical user interface for MRUI, a software package for quantitation of in vivo/medical magnetic resonance spectroscopy signals. Comput Biol Med. 2001;31(4):269-286. doi:10.1016/S0010-4825(01)00006-3 [doi]
11. Vanhamme L, Van Huffel S. AMARES: Advanced Method for Accurate, Robust and Efficient Spectral fitting of MRS data with use of prior knowledge. J Magn Reson. 1997;43(129):1-2. doi:10.1006/jmre.1997.1244 [doi]
12. Vandenborne K, Mccully K, Kakihira H, et al. Metabolic heterogeneity in human calf muscle during maximal exercise. Proc Natl Acad Sci U S A. 1991;88(13):5714-5718. doi:10.1073/pnas.88.13.5714 [doi]